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prof. I.J. (Jorg) van Bikker

prof. I.J. (Jorg) van Bikker

Associate Professor

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Research Output (36)

Dutch juvenile idiopathic arthritis patients, carers and clinicians create a research agenda together following the James Lind Alliance method:A study protocol

Schoemaker Casper G., Armbrust Wineke, Swart Joost F., Vastert Sebastiaan J., Van Loosdregt Jorg, Verwoerd Anouk, Whiting Caroline, Cowan Katherine, Olsder Wendy, Versluis Els, Van Vliet Rens, Fernhout Marlous J., Bookelman Sanne L., Cappon Jeannette, Van Den Berg J. Merlijn, Schatorjé Ellen, Muller Petra C.E.Hissink, Kamphuis Sylvia, De Boer Joke, Lelieveld Otto T.H.M., Van Der Net Janjaap, Jongsma Karin R., Van Rensen Annemiek, Dedding Christine, Wulffraat Nico M. 15 Sep 2018, In: Pediatric Rheumatology. 16

Transcriptional and epigenetic profiling of nutrient-deprived cells to identify novel regulators of autophagy

Peeters J. G.C., Picavet L. W., Coenen S. G.J.M., Mauthe M., Vervoort S. J., Mocholi E., de Heus C., Klumperman J., Vastert S. J., Reggiori F., Coffer P. J., Mokry M., van Loosdregt J. 28 Aug 2018, In: Autophagy. 15 , p. 98-112 15 p.

ARTHRITIS IS NOT A PREREQUISITE DISEASE MANIFESTATION FOR THE DIAGNOSIS OF SYSTEMIC JIA: RESULTS OF A PROSPECTIVE COHORT TRIAL USING RIL-1RA AS FIRST LINE TREATMENT WITH LONG TERM FOLLOW-UP

Ter Haar N. M., Leek A., El Idrissi A., Swart J. F., van Loosdregt J., Wulffraat N., de Roock S., Vastert S. Jun 2018, In: Annals of the Rheumatic Diseases. 77 , p. 1663-1663

Increased autophagy contributes to the inflammatory phenotype of juvenile idiopathic arthritis synovial fluid T cells

Peeters Janneke G. C., de Graeff Nienke, Lotz Martin, Albani Salvatore, de Roock Sytze, van Loosdregt Jorg 1 Oct 2017, In: Rheumatology (Oxford, England). 56 , p. 1694-1699 6 p.

Enhancers in autoimmune arthritis:Implications and therapeutic potential

Peeters Janneke G. C., Vastert Sebastiaan J, van Wijk Femke, van Loosdregt Jorg 30 Jun 2017, In: Arthritis & Rheumatology. 69 , p. 1925–1936 12 p.

Increased autophagy in CD4(+) T cells of rheumatoid arthritis patients results in T-cell hyperactivation and apoptosis resistance

van Loosdregt Jorg, Rossetti Maura, Spreafico Roberto, Moshref Maryam, Olmer Merissa, Williams Gary W, Kumar Pavanish, Copeland Dana, Pischel Ken, Lotz Martin, Albani Salvatore Dec 2016, In: European Journal of Immunology. 46 , p. 2862-2870 9 p.

A circulating reservoir of pathogenic-like CD4+ T cells shares a genetic and phenotypic signature with the inflamed synovial micro-environment

Spreafico Roberto, Rossetti Maura, van Loosdregt Jorg, Wallace Carol A, Massa Margherita, Magni-Manzoni Silvia, Gattorno Marco, Martini Alberto, Lovell Daniel J, Albani Salvatore Feb 2016, In: Annals of the Rheumatic Diseases. 75 , p. 459-465 7 p.

FOXP3 can modulate TAL1 transcriptional activity through interaction with LMO2

Fleskens V., Mokry M., van der Leun A. M., Huppelschoten S., Pals C. E G M, Peeters J., Coenen S., Cardoso B. A., Barata J. T., van Loosdregt J., Coffer P. J. 2016, In: Oncogene. 35 , p. 4141–4148 8 p.

Autoimmune disease-associated gene expression is reduced by BET-inhibition

Peeters Janneke G C, Vervoort Stephin J, Mijnheer Gerdien, de Roock Sytze, Vastert Sebastiaan J , Nieuwenhuis Edward E S, van Wijk Femke, Prakken Berent J, Mokry Michal, van Loosdregt Jorg 2016, In: Genomics data. 7 , p. 14-7 4 p.

Inhibition of Super-Enhancer Activity in Autoinflammatory Site-Derived T Cells Reduces Disease-Associated Gene Expression

Peeters Janneke G C, Vervoort Stephin J, Tan Sander C, Mijnheer Gerdien, de Roock Sytze, Vastert Sebastiaan J. , Nieuwenhuis Edward E S, van Wijk Femke, Prakken Berent J, Creyghton Menno P, Coffer Paul J, Mokry Michal, van Loosdregt Jorg 29 Sep 2015, In: Cell Reports [E]. 12 , p. 1986-1996 11 p.

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