prof. I.J. (Jorg) van Bikker
prof. I.J. (Jorg) van Bikker

- Center for Translational Immunology (CTI) Research
- Immuno/reuma onderzoek 3 (Loosdregt)
Research Programs
Biography
Biography
Jorg van Loosdregt (1981) obtained his PhD at the Molecular Immunology laboratory, University Medical Center Utrecht, The Netherlands. Here, he studied the regulation of the transcription factor FOXP3, which is crucial for both the differentiation and function of Regulatory T cells, and therefore for maintaining immune homeostasis. After completing his PhD program in 2011 (cum laude) Jorg moved to the Department of Translational Research, at the Sanford-Burnham Medical Institute in San Diego, USA, on a fellowship from the Dutch Arthritis Foundation. Here he investigated the role of autophagy in orchestrating effector T cell responses, with a focus on rheumatoid arthritis. Since December 2013 van Loosdregt is working in the laboratory for translational immunology (LTI) and Center for Molecular Medicine (CMM) where he is supported by a VENI fellowship. Here he uses a translational approach to study the molecular pathways that are deregulated in autoimmune diseases with the aim of identifying novel therapeutic strategies to treat these diseases.
Fellowship and Awards
2016: Wilhelmina Childrens hospital, fellowship €150.000
2015: Dutch Arthritis Foundation, fellowship €160.000
2014: NWO VENI, fellowship €250.000
2014: Wilhelmina Childrens hospital, fellowship €150.000
2013: NWO Graduate Program, fellowship €200.000
(together with J. Peeters and P. Coffer)
2012: Eureka translational medicine programme, scholarship €2.500
2012: Girard de Mielet van Coehoorn Foundation, prize €2.000
2012: Dutch Arthritis Foundation, fellowship €134.000
2011: Thesis defence honored Cum Laude
2010: Dutch Society of Immunology, travel grant €500
2009: UMC Utrecht, prize €500
Research Output (36)
Mijnheer Gerdien, Lutter Lisanne, Mokry Michal, van der Wal Marlot, Scholman Rianne, Fleskens Veerle, Pandit Aridaman, Tao Weiyang, Wekking Mark, Vervoort Stephin, Roberts Ceri, Petrelli Alessandra, Peeters Janneke G C, Knijff Marthe, de Roock Sytze, Vastert Sebastiaan, Taams Leonie S, van Loosdregt Jorg, van Wijk Femke Dec 2021, In: Nature Communications. 12 , p. 1-16
Angiolilli Chiara, Leijten Emmerik F A, Bekker Cornelis P J, Eeftink Ella, Giovannone Barbara, Nordkamp Michel Olde, van der Wal Marlot, Thijs Judith L, Vastert Sebastiaan J, van Wijk Femke, Radstake Timothy R D J, van Loosdregt Jorg 30 Jul 2021, In: Journal of Investigative Dermatology. 142 , p. 402-413 12 p.
Verwoerd Anouk, Armbrust Wineke, Cowan Katherine, van den Berg Lotte, de Boer Joke, Bookelman Sanne, Britstra Marjan, Cappon Jeannette, Certan Maria, Dedding Christine, van den Haspel Karin, Muller Petra Hissink, Jongsma Karin, Lelieveld Otto, van Loosdregt Jorg, Olsder Wendy, Rocha Johanna, Schatorjé Ellen, Schouten Natasja, Swart Joost F., Vastert Sebastiaan, Walter Margot, Schoemaker Casper G. 7 Apr 2021, In: Pediatric Rheumatology. 19
Samat Anoushka Ashok Kumar, van der Geest Jolijn, Vastert Sebastiaan J, van Loosdregt Jorg, van Wijk Femke 16 Feb 2021, In: Cells. 10 18 p.
Klionsky Daniel J, Abdel-Aziz Amal Kamal, Abdelfatah Sara, Abdellatif Mahmoud, Abdoli Asghar, Abel Steffen, Abeliovich Hagai, Abildgaard Marie H, Abudu Yakubu Princely, Acevedo-Arozena Abraham, Adamopoulos Iannis E, Adeli Khosrow, Adolph Timon E, Adornetto Annagrazia, Aflaki Elma, Agam Galila, Agarwal Anupam, Aggarwal Bharat B, Agnello Maria, Agostinis Patrizia, Agrewala Javed N, Agrotis Alexander, Aguilar Patricia V, Ahmad S Tariq, Ahmed Zubair M, Ahumada-Castro Ulises, Aits Sonja, Aizawa Shu, Akkoc Yunus, Akoumianaki Tonia, Akpinar Hafize Aysin, Al-Abd Ahmed M, Al-Akra Lina, Al-Gharaibeh Abeer, Alaoui-Jamali Moulay A, Alberti Simon, Alcocer-Gómez Elísabet, Alessandri Cristiano, Ali Muhammad, Alim Al-Bari M Abdul, Aliwaini Saeb, Alizadeh Javad, Almacellas Eugènia, Almasan Alexandru, Alonso Alicia, Lorenowicz Magdalena J, Manzoni Claudia, Reggiori Fulvio, van Loosdregt Jorg, Wang Yan, Jan 2021, In: Autophagy. 17 , p. 1-382 382 p.
Mijnheer G., Servaas N., Lutter L., Leong J. Y., Spierings E., Chen P., Petrelli A., Vastert S., de Boer R., Albani S., van Loosdregt J., Pandit A., van Wijk F. 2021, In: Clinical and Experimental Rheumatology. 39 , p. 1153-1154
ter Haar Nienke M., van Dijkhuizen E. H.Pieter, Swart Joost F., van Royen-Kerkhof Annet, el Idrissi Ayman, Leek Arjen P., de Jager Wilco, de Groot Mark C.H., Haitjema Saskia, Holzinger Dirk, Foell Dirk, van Loosdregt Jorg, Wulffraat Nico M., de Roock Sytze, Vastert Sebastiaan J. 8 Mar 2019, In: Arthritis & Rheumatology. 71 , p. 1163-1173 11 p.
Nijhuis Lotte, Peeters Janneke G.C., Vastert Sebastiaan J., Van Loosdregt Jorg 7 Feb 2019, In: Frontiers in Immunology. 10
Kumar Pavanish, Yao Leong Jing, Saidin Suzan, Paleja Bhairav, van Loosdregt Jorg, Chua Camillus, Arkachaisri Thaschawee, Consolaro Alessandro, Gattorno Marco, Martini Alberto, Pischel Ken D., Williams Gary W., Lotz Martin, Albani Salvatore 1 Nov 2018, In: Journal of Autoimmunity. 94 , p. 90-98 9 p.
Van Loosdregt Jorg, Coffer Paul J. 15 Oct 2018, In: Journal of Immunology. 201 , p. 2193-2200 8 p.