Back

drs. T.U. Polman

drs. T.U. Polman

Associate Professor - medical

Show full profile

Research Output (131)

Anti-tumor necrosis factor α targets protein kinase B/c-Akt-induced resistance of effector cells to suppression in juvenile idiopathic arthritis

Wehrens E.J.M., Vastert S.J., Mijnheer G., Meerding J., Klein M, Wulffraat N.M., Prakken A.B.J., van Wijk F. 2013, In: Arthritis and Rheumatism. 65 , p. 3279-3284 6 p.

Time to share

Wulffraat N.M., Vastert S.J., Share consortium [No Value] 2013, In: Pediatric Rheumatology. 11 , p. 5 1 p.

A phase II, multicenter, open-label study evaluating dosing and preliminary safety and efficacy of canakinumab in systemic juvenile idiopathic arthritis with active systemic features

Ruperto N., Quartier P., Wulffraat N.M., Woo P., Ravelli A., Mouy R., Bader-Meunier B., Vastert S.J., Noseda E., D'Ambrosio D., Lecot J., Chakraborty A.B., Martini A., Chioato A. 2012, In: Arthritis and Rheumatism. 64 , p. 557-67 11 p.

Decreased levels of sCD21 and sCD23 in blood of patients with systemic-juvenile arthritis, polyarticular-juvenile arthritis, and pauciarticular-juvenile arthritis

Singh A., Vastert S.J., Prakken A.B.J., Illges H. 2012, In: Rheumatology International. 32 , p. 1581-1587 7 p.

METHOTREXATE DOES NOT EXERT IMMUNOMODULATORY EFFECTS ON REGULATORY T CELLS BUT ON EFFECTOR T CELLS

Bulatovic Maja, Vastert Sebastiaan, de Jager Wilco, Verweij Frederiek, van Wijk Femke, Wulffraat Nico, Prakken Berent Mar 2011, In: Annals of the Rheumatic Diseases. 70 , p. A44-A44

Methotrexate does not exert immunomodulatory effects on regulatory T cells but on effector T cells

Bulatovic Maja, Vastert Sebastiaan, de Jager Wilco, Verweij Frederiek, van Wijk Femke, Wulffraat Nico, Prakken Berent 2011, In: Clinical and Experimental Rheumatology. 29 , p. 448-448

Anakinra Treatment prior to Steroids In Newly Diagnosed Systemic Onset JIA; Changing the Biology?

De Jager W., Vastert S. J., Holzinger D., Kuis W., Prakken B. J., Wulffraat N. M. 2011, In: Clinical and Experimental Rheumatology. 29 , p. 375-376

Functional human regulatory T cells fail to control autoimmune inflammation due to PKB/c-akt hyperactivation in effector cells

Wehrens E.J.M., Mijnheer G., Duurland C.L., Klein M., Meerding J.M., van Loosdregt J., de Jager W., Sawitzki B., Coffer P.J, Vastert S.J., Prakken A.B.J., van Wijk F. 2011, In: Blood. 118 , p. 3538-3548 10 p.

Development of Inflammatory Bowel Disease in Patients with Juvenile Idiopathic Arthritis Treated with Etanercept

van Dijken T.D., Vastert S.J., Gerloni V., Pontikaki I., Linnemann K., Girschick H., Armbrust W., Minden K., Prince F.H., Kokke F.T.M., Nieuwenhuis E.E.S., Horneff G., Wulffraat N.M. 2011, In: Journal of Rheumatology. 38 , p. 1441-1446 6 p.

FOXP3+ CD4+ Tregs lose suppressive potential but remain anergic during transient inflammation in human

Schadenberg A.W.L., Vastert S.J., Evens F.C.M., Kuis W., van Vught A.J., Jansen N.J.G., Prakken A.B.J. 2011, In: European Journal of Immunology. 41 , p. 1132-1142 11 p.

Thank you for your review!

Has this information helped you?

Please tell us why, so that we can improve our website.

Working at UMC Utrecht

Contact

Emergency?

Directions

Appointments

Practical

umcutrecht.nl uses cookies

This website uses cookies This website displays videos from, among others, YouTube. Such parties place cookies (third-party cookies). If you do not want these cookies, you can indicate that here. We also place cookies ourselves to improve our site.

Read more about the cookie policy

Agree No, rather not