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ir. Z.A. (Michal) Otterloo

ir. Z.A. (Michal) Otterloo

Associate Professor

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Research Output (102)

Sex-Stratified Gene Regulatory Networks Reveal Female Key Driver Genes of Atherosclerosis Involved in Smooth Muscle Cell Phenotype Switching

Hartman Robin J G, Owsiany Katie, Ma Lijiang, Koplev Simon, Hao Ke, Slenders Lotte, Civelek Mete, Mokry Michal, Kovacic Jason C, Pasterkamp Gerard, Owens Gary, Björkegren Johan L M, den Ruijter Hester M 16 Feb 2021, In: Circulation. 143 , p. 713-726 14 p.

Sex-dependent gene regulation of human atherosclerotic plaques by DNA methylation and transcriptome integration points to smooth muscle cell involvement in women

Hartman R., Siemelink M., Haitjema S., Dekkers K. F., Slenders L., Boltjes A., Mokry M., Timmerman N., De Borst G. J., Heijmans B. T., Asselbergs F. W., Pasterkamp G., Van der Laan S. W., Den Ruijter H. M. 29 Jan 2021,

Regulation of a progenitor gene program by SOX4 is essential for mammary tumor proliferation

Roukens M Guy, Frederiks Cynthia L, Seinstra Danielle, Braccioli Luca, Khalil Antoine A, Pals Cornelieke, De Neck Simon, Bornes Laura, Beerling Evelyne, Mokry Michal, de Bruin Alain, Westendorp Bart, van Rheenen Jacco, Coffer Paul J 2021, In: Oncogene. 40 , p. 6343-6353 11 p.

Proteomic and Functional Studies Reveal Detyrosinated Tubulin as Treatment Target in Sarcomere Mutation-Induced Hypertrophic Cardiomyopathy

Schuldt Maike, Pei Jiayi, Harakalova Magdalena, Dorsch Larissa M, Schlossarek Saskia, Mokry Michal, Knol Jaco C, Pham Thang V, Schelfhorst Tim, Piersma Sander R, Dos Remedios Cris, Dalinghaus Michiel, Michels Michelle, Asselbergs Folkert W, Moutin Marie-Jo, Carrier Lucie, Jimenez Connie R, van der Velden Jolanda, Kuster Diederik W D 2021, In: Circulation. Heart Failure. 14 , p. 39-55

A Unique Monocyte Transcriptome Discriminates Sickle Cell Disease From Other Hereditary Hemolytic Anemias and Shows the Particular Importance of Lipid and Interferon Signaling

van Vuren Annelies, van Straaten Stéphanie, Mokry Michal, van Wijk Richard, van Beers Eduard 17 Dec 2020, In: HemaSphere. 5 , p. 1-4

Prime editing for functional repair in patient-derived disease models

Schene Imre F, Joore Indi P, Oka Rurika, Mokry Michal, van Vugt Anke H M, van Boxtel Ruben, van der Doef Hubert P J, van der Laan Luc J W, Verstegen Monique M A, van Hasselt Peter M, Nieuwenhuis Edward E S, Fuchs Sabine A 1 Dec 2020, In: Nature Communications. 11

Developmental programming in human umbilical cord vein endothelial cells following fetal growth restriction

Terstappen Fieke, Calis Jorg J A, Paauw Nina D, Joles Jaap A, van Rijn Bas B, Mokry Michal, Plösch Torsten, Lely A Titia Dec 2020, In: Clinical Epigenetics. 12

Functional investigation of the coronary artery disease gene SVEP1

Winkler Michael J, Müller Philipp, Sharifi Amin M, Wobst Jana, Winter Hanna, Mokry Michal, Ma Lijiang, van der Laan Sander W, Pang Shichao, Miritsch Benedikt, Hinterdobler Julia, Werner Julia, Stiller Barbara, Güldener Ulrich, Webb Tom R, Asselbergs Folkert W, Björkegren Johan L M, Maegdefessel Lars, Schunkert Heribert, Sager Hendrik B, Kessler Thorsten Dec 2020, In: Basic Research in Cardiology. 115 , p. 1-15

Transcriptome of airway neutrophils reveals an interferon response in life-threatening respiratory syncytial virus infection

Besteman Sjanna B., Callaghan Amie, Langedijk Annefleur C., Hennus Marije P., Meyaard Linde, Mokry Michal, Bont Louis J., Calis Jorg J.A. Nov 2020, In: Clinical Immunology. 220 , p. 1-10

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