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prof. C.D.D. (Paul) Mager

prof. C.D.D. (Paul) Mager

Full Professor

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Research Output (182)

Regulation of a progenitor gene program by SOX4 is essential for mammary tumor proliferation

Roukens M Guy, Frederiks Cynthia L, Seinstra Danielle, Braccioli Luca, Khalil Antoine A, Pals Cornelieke, De Neck Simon, Bornes Laura, Beerling Evelyne, Mokry Michal, de Bruin Alain, Westendorp Bart, van Rheenen Jacco, Coffer Paul J 2021, In: Oncogene. 40 , p. 6343-6353 11 p.

C/EBPɑ is crucial determinant of epithelial maintenance by preventing epithelial-to-mesenchymal transition

Lourenço Ana Rita, Roukens M. Guy, Seinstra Danielle, Frederiks Cynthia L., Pals Cornelieke E., Vervoort Stephin J., Margarido Andreia S., van Rheenen Jacco, Coffer Paul J. 7 Feb 2020, In: Nature Communications. 11 , p. 1-18

Transcriptomic and Epigenomic Profiling of Histone Deacetylase Inhibitor Treatment Reveals Distinct Gene Regulation Profiles Leading to Impaired Neutrophil Development

Govers Anita M A P, Wiggers Caroline R M, van Boxtel Ruben, Mokry Michal, Nieuwenhuis Edward E S, Creyghton Menno P, Bartels Marije, Coffer Paul J Aug 2019, In: HemaSphere. 3

Epigenetic drug screen identifies the histone deacetylase inhibitor NSC3852 as a potential novel drug for the treatment of pediatric acute myeloid leukemia

Wiggers Caroline R M, Govers Anita M A P, Lelieveld Daphne, Egan David A, Zwaan C Michel, Sonneveld Edwin, Coffer Paul J, Bartels Marije 1 May 2019, In: Pediatric Blood & Cancer. 66

Nemo-like Kinase Drives Foxp3 Stability and Is Critical for Maintenance of Immune Tolerance by Regulatory T Cells

Fleskens Veerle, Minutti Carlos M., Wu Xingmei, Wei Ping, Pals Cornelieke E.G.M., McCrae James, Hemmers Saskia, Groenewold Vincent, Vos Harm Jan, Rudensky Alexander, Pan Fan, Li Huabin, Zaiss Dietmar M., Coffer Paul J. 26 Mar 2019, In: Cell Reports. 26 , p. 3600-3612.e6

Global transcriptional analysis identifies a novel role for SOX4 in tumor-induced angiogenesis

Vervoort Stephin J., de Jong Olivier G., Guy Roukens M., Frederiks Cynthia L., Vermeulen Jeroen F., Lourenço Ana Rita, Bella Laura, Vidakovic Ana Tufegdzic, Sandoval José L., Moelans Cathy, van Amersfoort Miranda, Dallman Margaret J., Bruna Alejandra, Caldas Carlos, Nieuwenhuis Edward, van der Wall Elsken, Derksen Patrick, van Diest Paul, Verhaar Marianne C., Lam Eric W.F., Mokry Michal, Coffer Paul J. 3 Dec 2018, In: eLife. 7

SOX4 inhibits oligodendrocyte differentiation of embryonic neural stem cells in vitro by inducing Hes5 expression

Braccioli Luca, Vervoort Stephin J., Puma Gianmarco, Nijboer Cora H., Coffer Paul J. 1 Dec 2018, In: Stem Cell Research. 33 , p. 110-119 10 p.

The role of WNT signaling in mature T cells:T cell factor is coming home

Van Loosdregt Jorg, Coffer Paul J. 15 Oct 2018, In: Journal of Immunology. 201 , p. 2193-2200 8 p.

SOX4 can redirect TGF-β-mediated SMAD3-transcriptional output in a context-dependent manner to promote tumorigenesis

Vervoort Stephin J., Lourenço Ana Rita, Tufegdzic Vidakovic Ana, Mocholi Enric, Sandoval José L., Rueda Oscar M., Frederiks Cynthia, Pals Cornelieke, Peeters Janneke G.C., Caldas Carlos, Bruna Alejandra, Coffer Paul J. 12 Oct 2018, In: Nucleic Acids Research. 46 , p. 9578-9590 13 p.

PD-1<sup>+</sup>CD8<sup>+</sup> T cells are clonally expanding effectors in human chronic inflammation

Petrelli Alessandra, Mijnheer Gerdien, Hoytema Van Konijnenburg David P., Van Der Wal Maria M., Giovannone Barbara, Mocholi Enric, Vazirpanah Nadia, Broen Jasper C., Hijnen Dirkjan, Oldenburg Bas, Coffer Paul J., Vastert Sebastian J., Prakken Berent J., Spierings Eric, Pandit Aridaman, Mokry Michal, Van Wijk Femke 1 Oct 2018, In: Journal of Clinical Investigation. 128 , p. 4669-4681 13 p.

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