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ir. O. Kaagman

ir. O. Kaagman

Full Professor

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Research Output (137)

Ethical challenges for pediatric liver organoid transplantation

Schneemann Sarah A, Boers Sarah N, van Delden Johannes J M, Nieuwenhuis Edward E S, Fuchs Sabine A, Bredenoord Annelien L 15 Jul 2020, In: Science translational medicine. 12 , p. 1-3

H3K27ac acetylome signatures reveal the epigenomic reorganization in remodeled non-failing human hearts

Pei Jiayi, Harakalova Magdalena, Treibel Thomas A, Lumbers R Thomas, Boukens Bastiaan J, Efimov Igor R, van Dinter Jip T, González Arantxa, López Begoña, El Azzouzi Hamid, van den Dungen Noortje, van Dijk Christian G M, Krebber Merle M, den Ruijter Hester M, Pasterkamp Gerard, Duncker Dirk J, Nieuwenhuis Edward E S, de Weger Roel, Huibers Manon M, Vink Aryan, Moore Jason H, Moon James C, Verhaar Marianne C, Kararigas Georgios, Mokry Michal, Asselbergs Folkert W, Cheng Caroline 14 Jul 2020, In: Clinical Epigenetics. 12 18 p.

Quantifying lymphocyte vacuolization serves as a measure of CLN3 disease severity

Kuper Willemijn F E, Oostendorp Marlies, van den Broek Brigitte T A, van Veghel Karin, Nonkes Lourens J P, Nieuwenhuis Edward E S, Fuchs Sabine A, Veenendaal Tineke, Klumperman Judith, Huisman Albert, Nierkens Stefan, van Hasselt Peter M Jul 2020, In: JIMD Reports. 54 , p. 87-97 11 p.

Very Early Onset Inflammatory Bowel Disease:A Clinical Approach With a Focus on the Role of Genetics and Underlying Immune Deficiencies

Ouahed Jodie, Spencer Elizabeth, Kotlarz Daniel, Shouval Dror S, Kowalik Matthew, Peng Kaiyue, Field Michael, Grushkin-Lerner Leslie, Pai Sung-Yun, Bousvaros Athos, Cho Judy, Argmann Carmen, Schadt Eric, Mcgovern Dermot P B, Mokry Michal, Nieuwenhuis Edward, Clevers Hans, Powrie Fiona, Uhlig Holm, Klein Christoph, Muise Aleixo, Dubinsky Marla, Snapper Scott B 3 Dec 2019, In: Inflammatory bowel diseases. 26 , p. 820-842 23 p.

AML Subtype Is a Major Determinant of the Association between Prognostic Gene Expression Signatures and Their Clinical Significance

Wiggers Caroline R M, Baak Mirna L, Sonneveld Edwin, Nieuwenhuis Edward E S, Bartels Marije, Creyghton Menno P 10 Sep 2019, In: Cell Reports. 28 , p. 2866-2877.e5

Transcriptomic and Epigenomic Profiling of Histone Deacetylase Inhibitor Treatment Reveals Distinct Gene Regulation Profiles Leading to Impaired Neutrophil Development

Govers Anita M A P, Wiggers Caroline R M, van Boxtel Ruben, Mokry Michal, Nieuwenhuis Edward E S, Creyghton Menno P, Bartels Marije, Coffer Paul J Aug 2019, In: HemaSphere. 3

DGAT2 partially compensates for lipid-induced ER stress in human DGAT1-deficient intestinal stem cells[S]

van Rijn Jorik M, van Hoesel Marliek, de Heus Cecilia, van Vugt Anke H M, Klumperman Judith, Nieuwenhuis Edward, Houwen Roderick H J, Middendorp Sabine 17 Jul 2019, In: Journal of Lipid Research. 60 , p. 1787-1800 14 p.

Motor function impairment is an early sign of CLN3 disease

Kuper Willemijn F.E., Van Alfen Claudia, Van Eck Linda, Huijgen Barbara C.H., Nieuwenhuis Edward E.S., Van Brussel Marco, Van Hasselt Peter M. 16 Jul 2019, In: Neurology. 93 , p. e293-e297

Integrated analysis of transcriptional regulation in PLN R14del cardiomyopathy

Pei J., Harakalova M., Nagyova E., Gho J. M. I. H., Sepehrkhouy S., van Dinter J., van Mil A., Buijsrogge M. P., de Jonge N., Huibers M. M., Nieuwenhuis E. E. S., den Ruijter H. M., Pasterkamp G., Doevendans P. A., Hajjar R., Mercola M., Sluijter J. P. G., de Weger R. A., Cheng C., Vink A., Mokry M., Asselbergs F. W. Jul 2019, In: European Journal of Human Genetics. 27 , p. 790-791

Human Fetal TNF-α-Cytokine-Producing CD4+ Effector Memory T Cells Promote Intestinal Development and Mediate Inflammation Early in Life

Schreurs Renée R C E, Baumdick Martin E, Sagebiel Adrian F, Kaufmann Max, Mokry Michal, Klarenbeek Paul L, Schaltenberg Nicola, Steinert Fenja L, van Rijn Jorik M, Drewniak Agata, The Sarah-May M L, Bakx Roel, Derikx Joep P M, de Vries Niek, Corpeleijn Willemijn E, Pals Steven T, Gagliani Nicola, Friese Manuel A, Middendorp Sabine, Nieuwenhuis Edward E S, Reinshagen Konrad, Geijtenbeek Teunis B H, van Goudoever Johannes B, Bunders Madeleine J 19 Feb 2019, In: Immunity. 50 , p. 462-476.e1-e8

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