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drs. P.Q.Q. (Elly) Hegeman

drs. P.Q.Q. (Elly) Hegeman

Full Professor

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Research Output (184)

Reactive astrocyte nomenclature, definitions, and future directions

Escartin Carole et al. Mar 2021, In: Nature Neuroscience. 24 , p. 312-325 14 p.

Viscoelastic mapping of mouse brain tissue:Relation to structure and age

Antonovaite Nelda, Hulshof Lianne A., Hol Elly M., Wadman Wytse J., Iannuzzi Davide Jan 2021, In: Journal of the Mechanical Behavior of Biomedical Materials. 113 11 p.

A loss of mature microglial markers without immune activation in schizophrenia

Snijders Gijsje J.L.J., van Zuiden Welmoed, Sneeboer Marjolein A.M., Berdenis van Berlekom Amber, van der Geest Astrid T., Schnieder Tatiana, MacIntyre Donald J.M., Hol Elly M., Kahn René S., de Witte Lot D. 2021, In: GLIA. 69 , p. 1251-1267 17 p.

Physiological and Pathological Ageing of Astrocytes in the Human Brain

Verkerke Marloes, Hol Elly M., Middeldorp Jinte 2021, In: Neurochemical Research. 46 , p. 2662-2675 14 p.

Reactive astrocytes as treatment targets in Alzheimer's disease—Systematic review of studies using the APPswePS1dE9 mouse model

Smit Tamar, Deshayes Natasja A.C., Borchelt David R., Kamphuis Willem, Middeldorp Jinte, Hol Elly M. 2021, In: GLIA. 69 , p. 1852-1881 30 p.

Loss of lamin-B1 and defective nuclear morphology are hallmarks of astrocyte senescence in vitro and in the aging human hippocampus

Matias Isadora, Diniz Luan Pereira, Damico Isabella Vivarini, Araujo Ana Paula Bergamo, Neves Laís da Silva, Vargas Gabriele, Leite Renata E P, Suemoto Claudia K, Nitrini Ricardo, Jacob-Filho Wilson, Grinberg Lea T, Hol Elly M, Middeldorp Jinte, Gomes Flávia Carvalho Alcantara 2021, In: Aging Cell. 21 , p. 1-18

Investigation of glial fibrillary acidic protein (GFAP) in body fluids as a potential biomarker for glioma:a systematic review and meta-analysis

van Asperen Jessy V., Fedorushkova Daria M., Robe Pierre A.J.T., Hol Elly M. 2021, In: Biomarkers. 27 , p. 1-12 12 p.

How the COVID-19 pandemic highlights the necessity of animal research (vol 30, pg R1014, 2020):How the COVID-19 pandemic highlights the necessity of animal research (Current Biology (2020) 30(18) (R1014–R1018), (S0960982220311842), (10.1016/j.cub.2020.08.030))

Genzel Lisa, Adan Roger, Berns Anton, van den Beucken Jeroen J.J.P., Blokland Arjan, Boddeke Erik H.W.G.M., Bogers Willy M., Bontrop Ronald, Bulthuis R., Bousema Teun, Clevers Hans, Coenen Tineke C.J.J., van Dam Anne Marie, Deen Peter M.T., van Dijk K. W., Eggen Bart J.L., Elgersma Ype, Erdogan Izel, Englitz Bernhard, Fentener van Vlissingen J. Martje, la Fleur Susanne, Fouchier Ron, Fitzsimons Carlos P., Frieling Wilbert, Haagmans Bart, Heesters Balthasar A., Henckens Marloes J.A.G., Herfst Sander, Hol Elly, van den Hove Daniel, de Jonge Marien I., Jonkers Jos, Joosten Leo A.B., Kalsbeek Andries, Kamermans Maarten, Kampinga Harm H., Kas Martien J., Keijer Jaap, Kersten Sander, Kiliaan Amanda J., Kooij Taco W.A., Kooijman Sander, Koopman Werner J.H., Lesscher Heidi M.B., Meye Frank J., Mul Joram D., Pasterkamp R. Jeroen, van Rheenen Jacco, Vanderschuren Louk J.M.J., Homberg Judith R., 2 Nov 2020, In: Current Biology. 30 , p. 4328-4328 1 p.

Profiling Microglia From Alzheimer’s Disease Donors and Non-demented Elderly in Acute Human Postmortem Cortical Tissue

Alsema Astrid M., Jiang Qiong, Kracht Laura, Gerrits Emma, Dubbelaar Marissa L., Miedema Anneke, Brouwer Nieske, Hol Elly M., Middeldorp Jinte, van Dijk Roland, Woodbury Maya, Wachter Astrid, Xi Simon, Möller Thomas, Biber Knut P., Kooistra Susanne M., Boddeke Erik W.G.M., Eggen Bart J.L. 28 Oct 2020, In: Frontiers in Molecular Neuroscience. 13 , p. 1-14

How the COVID-19 pandemic highlights the necessity of animal research

Genzel Lisa, Adan Roger, Berns Anton, van den Beucken Jeroen, Blokland Arjan, Boddeke Erik H.W.G.M., Bogers Willy M., Bontrop Ronald, Bulthuis R., Bousema Teun, Clevers Hans, Coenen Tineke C.J.J., Dam Anne Marie van, Deen Peter M.T., van Dijk K. W., Eggen Bart J.L., Elgersma Ype, Erdogan Izel, Englitz Bernard, Fentener van Vlissingen J. Martje, la Fleur Susanne, Fouchier Ron, Fitzsimons Carlos P., Frieling Wilbert, Haagmans Bart, Heesters Balthasar A., Henckens Marloes, Herfst Sander, Hol Elly, van den Hove Daniel, de Jonge Marien I., Jonkers Jos, Joosten Leo A.B., Kalsbeek Andries, Kamermans Maarten, Kampinga Harm H., Kas Martien J., Keijer J., Kersten Sander, Kiliaan Amanda J., Kooij Taco W.A., Kooijman Sander, Koopman Werner J.H., Lesscher Heidi, Meye Frank J., Mul Joram D., Pasterkamp R. Jeroen, van Rheenen Jacco, Vanderschuren Louk J.M.J., Homberg Judith R., 21 Sep 2020, In: Current Biology. 30 , p. R1014-R1018

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