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drs. X.Y.Y. Breugelmans

drs. X.Y.Y. Breugelmans

Associate Professor

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Research Output (22)

Evaluating in vivo efficacy - Toxicity profile of TEG001 in humanized mice xenografts against primary human AML disease and healthy hematopoietic cells

Johanna Inez, Straetemans Trudy, Heijhuurs Sabine, Aarts-Riemens Tineke, Norell Håkan, Bongiovanni Laura, De Bruin Alain, Sebestyen Zsolt, Kuball Jürgen 12 Mar 2019, In: Journal for ImmunoTherapy of Cancer. 7

GMP-grade manufacturing of T cells engineered to express a defined γδTCR

Straetemans Trudy, Kierkels Guido J.J., Doorn Ruud, Jansen Koen, Heijhuurs Sabine, dos Santos Joao M., van Muyden Anna D.D., Vie Henri, Clemenceau Béatrice, Raymakers Reinier, de Witte Moniek, Sebestyén Zsolt, Kuball Jürgen 30 May 2018, In: Frontiers in Immunology [E]. 9

Cellular immunotherapy on primary multiple myeloma expanded in a 3D bone marrow niche model

Braham Maaike V.J., Minnema Monique C., Aarts Tineke, Sebestyen Zsolt, Straetemans Trudy, Vyborova Anna, Kuball Jurgen, Öner F. Cumhur, Robin Catherine, Alblas Jacqueline 12 Feb 2018, In: OncoImmunology. 7

Prevention of Vγ9Vδ2 T Cell Activation by a Vγ9Vδ2 TCR Nanobody

de Bruin Renée C G, Stam Anita G M, Vangone Anna, van Bergen En Henegouwen Paul M P, Verheul Henk M W, Sebestyen Z, Kuball Jürgen, Bonvin Alexandre M J J, de Gruijl Tanja D, van der Vliet Hans J 1 Jan 2017, In: Journal of Immunology. 198 , p. 308-317 10 p.

A bispecific nanobody approach to leverage the potent and widely applicable tumor cytolytic capacity of Vγ9Vδ2-T cells

de Bruin Renée C G, Veluchamy John P., Lougheed Sinéad M, Schneiders Famke L., Lopez-Lastra Silvia, Lameris Roeland, Stam Anita G M, Sebestyen Zsolt, Kuball Jürgen, Molthoff Carla F M, Hooijberg Erik, Roovers Rob C., Santo James P.Di, van Bergen En Henegouwen Paul M P, Verheul Henk M. W., de Gruijl Tanja D, van Vliet Hans J 2017, In: OncoImmunology. 7 , p. e1375641

RhoB Mediates Phosphoantigen Recognition by Vγ9Vδ2 T Cell Receptor

Sebestyen Zsolt, Scheper Wouter, Vyborova Anna, Gu Siyi, Rychnavska Zuzana, Schiffler Marleen, Cleven Astrid, Chéneau Coraline, van Noorden Martje, Peigné Cassie-Marie, Olive Daniel, Lebbink Robert Jan, Oostvogels Rimke, Mutis Tuna, Schuurhuis Gerrit Jan, Adams Erin J, Scotet Emmanuel, Kuball Jürgen 2016, In: Cell Reports [E]. 15 , p. 1973-1985 13 p.

Pre-clinical evaluation of CD38 chimeric antigen receptor engineered T cells for the treatment of multiple myeloma

Drent Esther, Groen Richard W.J., Noort Willy A, Themeli Maria, Lammerts van Bueren Jeroen J, Parren Paul W H I, Kuball Jürgen, Sebestyen Zsolt, Yuan Huipin, de Bruijn Joost, van de Donk Niels W C J, Martens Anton C M, Lokhorst Henk M, Mutis Tuna 2016, In: Haematologica. 101 , p. 616-625 10 p.

Untouched GMP-ready purified engineered immune cells to treat cancer

Straetemans Trudy, Gründer Cordula, Heijhuurs Sabine, Hol Samantha, Slaper-Cortenbach Ineke, Bönig Halvard, Sebestyen Zsolt, Kuball Jürgen 1 Sep 2015, In: Clinical Cancer Research. 21 , p. 3957-3968 12 p.

Hunting for clinical translation with innate-like immune cells and their receptors

Scheper W, Gründer C, Straetemans T, Sebestyen Z, Kuball J Jun 2014, In: Leukemia. 28 , p. 1181-1190 10 p.

Cancer Immunotherapy Using γδT Cells: Dealing with Diversity.

Scheper W.A., Sebestyen Z., Kuball J.H.E. 2014, In: Frontiers in Immunology [E]. 5 , p. 601-601 1 p.

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