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Cardio-Immunology

Cardio-Immunology

Research Topics uitklapper, klik om te openen

For further reading see:

https://www.sluijterlab.com/auto-immunity-in-heart-failure

Key Publications uitklapper, klik om te openen

Immunomodulation in Heart Failure with Preserved Ejection Fraction: Current State and Future Perspectives.

Kessler EL, Oerlemans MIFJ, van den Hoogen P, Yap C, Sluijter JPG, de Jager SCA.J Cardiovasc Transl Res. 2021 Feb;14(1):63-74. doi: 10.1007/s12265-020-10026-3. Epub 2020 May 22.PMID: 32444946 Free PMC article. Review.

The therapeutic potential of targeting CD40-TRAF6 pathway in cardiovascular Diseases.

Bosch L, de Haan JJ, Seijkens TTP, van Tiel CM, Brans MAD, Pasterkamp G, Lutgens E, de Jager SCA.Int J Cardiol. 2020 Feb 1;300:220. doi: 10.1016/j.ijcard.2019.09.013.

Potential of mesenchymal- and cardiac progenitor cells for therapeutic targeting of B-cells and antibody responses in end-stage heart failure.

van den Hoogen P, de Jager SCA, Mol EA, Schoneveld AS, Huibers MMH, Vink A, Doevendans PA, Laman JD, Sluijter JPG.PLoS One. 2019 Dec 31;14(12):e0227283. doi: 10.1371/journal.pone.0227283. eCollection 2019.

Increased circulating IgG levels, myocardial immune cells and IgG deposits support a role for an immune response in pre- and end-stage heart failure.

van den Hoogen P, de Jager SCA, Huibers MMH, Schoneveld AH, Puspitasari YM, Valstar GB, Oerlemans MIFJ, de Weger RA, Doevendans PA, den Ruijter HM, Laman JD, Vink A, Sluijter JPG.J Cell Mol Med. 2019 Nov;23(11):7505-7516. doi: 10.1111/jcmm.14619. Epub 2019 Sep 26.

Targeting Inflammation after Myocardial Infarction: A Therapeutic Opportunity for Extracellular Vesicles?

Viola M, de Jager SCA, Sluijter JPG.Int J Mol Sci. 2021 Jul 22;22(15):7831. doi: 10.3390/ijms22157831.

Requirements for Proper Immunosuppressive Regimens to Limit Translational Failure of Cardiac Cell Therapy in Preclinical Large Animal Models.

Demkes EJ, Rijken S, Szymanski MK, Hoefer IE, Sluijter JPG, de Jager SCA.J Cardiovasc Transl Res. 2021 Feb;14(1):88-99. doi: 10.1007/s12265-020-10035-2. Epub 2020 May 31.

Facilities Involved uitklapper, klik om te openen

HELPFul, Utrecht hartenbank

Contact uitklapper, klik om te openen

Saskia de Jager, s.c.a.dejager@umcutrecht.nl

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