dr. Y.Z.Z. (Martin) Spoolder

dr. Y.Z.Z. (Martin) Spoolder

Associate Professor
dr. Y.Z.Z. (Martin) Spoolder
  • Experimental Clinical Physics Radiotherapy



Martin Fast studied physics at the University of Heidelberg (2005-2010). From 2010-2013 he conducted his PhD studies on “New Methods for Motion Management During Radiation Therapy” at the German Cancer Research Center in Heidelberg. After postdoc appointments at The Institute of Cancer Research - Royal Marsden hospital in London (2013-2016) and the Netherlands Cancer Institute - Antoni van Leeuwenhoek hospital (2017-2019), Dr Fast was appointed as associate professor in the radiotherapy department of the UMC Utrecht in 2019. Dr Fast’s main research interest is the development of MRI-guided real-time adaptive radiotherapy. He is currently the (co-)author of approximately 45 peer-reviewed publications with more than 1200 citations. A full list of publications is available on GoogleScholar.

Grant awards:

  • NWO OTP #19484 MEGAHERTZ. 2022-2027. EUR 1,540,000 (PI)
  • NWO VIDI #17515 BREATHE EASY. 2019-2024. EUR 800,000 (PI)
  • EU H2020 #945119 STOPSTORM. 2021-2027. EUR 7,161,000 (work package leader and management board member)

PhD students:

  • Osman Akdag (Cardiac radioablation & MRI)
  • Frederique van Gameren (Abdominothoracic MRI)
  • Katrinus Keijnemans (4D-MRI)
  • Luuk van der Pol (Cardiac sparing & STOPSTORM)
  • Prescilla Uijtewaal (MLC tracking)


  • Tom Bosma (MRI coil development)

Research Output (40)

First experimental exploration of real-time cardiorespiratory motion management for future stereotactic arrhythmia radioablation treatments on the MR-linac

Akdag Osman, Borman Pim T S, Woodhead Peter L, Uijtewaal Prescilla, Mandija Stefano, van Asselen Bram, Verhoeff Joost J C, Raaymakers Bas W, Fast Martin F 21 Feb 2022, In: Physics in medicine and biology. 67 , p. 1-14

Feasibility of cardiac-synchronized quantitative T1 and T2 mapping on a hybrid 1.5 Tesla magnetic resonance imaging and linear accelerator system

Akdag Osman, Mandija Stefano, van Lier Astrid L H M W, Borman PTS, Schakel Tim, Alberts Eveline, van der Heide Oscar, Hassink Rutger J, Verhoeff Joost J C, Mohamed Hoesein Firdaus A A, Raaymakers Bas W, Fast Martin F Jan 2022, In: Physics and Imaging in Radiation Oncology. 21 , p. 153-159 7 p.

Cardiac-Synchronized T1 mapping on the Unity MR-linac to guide STereotactic Arrhythmia Radioablation

Mandija S., Akdag O., van Lier A., Borman P., Schakel T., Alberts E., van der Heide O., Hassink R., Alings M., Verhoeff J., Mohamed Hoesein F., Fast M. Aug 2021, In: Radiotherapy and Oncology. 161 , p. S408-S409

Automatic PTV margin determination for midposition-based lung SBRT planning on the Unity MR-linac

Ligtenberg H., Hackett S., Merckel L. G., Snoeren L., Kontaxis C., Zachiu C., Bol G., Verhoeff J. J., Fast M. F. Aug 2021, In: Radiotherapy and Oncology. 161 , p. S697-S698

Cardiac radioablation

Fast M. Aug 2021, In: Radiotherapy and Oncology. 161 , p. S457-S458

Left-ventricular MRI navigation: a novel approach for motion-free thoracic and cardiac radiotherapy

van Lier A., Akdag O., Mandija S., Borman P., Alberts E., Fast M. Aug 2021, In: Radiotherapy and Oncology. 161 , p. S517-S518

Feasibility of stereotactic body radiotherapy of (ultra)central lung tumors using an 1.5 T MR-linac

Merckel L., Hackett S., van Lier A., van den Dobbelsteen M., Rasing M., Snoeren L., van Es C., Fast M., van Rossum P., Verhoeff J. Aug 2021, In: Radiotherapy and Oncology. 161 , p. S963-S964

Real-time cardiorespiratory motion management for MRI-guided stereotactic arrythmia radioablation

Akdag O., Borman P., Uijtewaal P., Woodhead P., Kok J., Van Asselen B., Raaymakers B., Fast M. Aug 2021, In: Radiotherapy and Oncology. 161 , p. S384-S385

First VMAT delivery with MLC-tracking for single and multi fraction lung SBRT on a Unity MR-linac

Uijtewaal P., Borman P., Woodhead P., Kontaxis C., Hackett S., Verhoeff J., Raaymakers B., Fast M. Aug 2021, In: Radiotherapy and Oncology. 161 , p. S479-S480

The delta index: a novel metric to assess dose accumulation uncertainty in MR-guided radiotherapy

van den Dobbelsteen M., Hackett S., Verhoeff J., Merckel L., van Es C., Snoeren L., Kontaxis C., Fast M. Aug 2021, In: Radiotherapy and Oncology. 161 , p. S700-S702

All research output

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