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dr. S.A.W. (R.H.) Sluijter BSc

dr. S.A.W. (R.H.) Sluijter BSc

Full Professor

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Research Output (144)

Quaternary structure of the human Cdt1-Geminin complex regulates DNA replication licensing

de Marco V, Gillespie P.J., Li A., Karantzelis N., Christodoulou E., Klompmaker R., van Gerwen S.J.C., Fish A., Pethoukhov M.V., Ilou M.S., Lygerou Z, Medema R.H., Blow J.J., Svergun D.I., Taraviras S., Perrakis A. 2009, In: Proceedings of the National Academy of Sciences of the United States of America. 106 , p. 19807-19812 6 p.

P18 is a tumor suppressor gene involved in human medullary thyroid carcinoma and pheochromocytoma development.

van Veelen W., Klompmaker R., Gloerich M., van Gasteren C.J.R., Kalkhoven E., Berger R., Lips C.J.M., Medema R.H., Höppener J.W.M., Acton D.S. 2009, In: International Journal of Cancer. 124 , p. 339-345 6 p.

Relaying the checkpoint signal from kinetochore to APC/C.

Medema R.H. 2009, In: Developmental Cell. 16 , p. 6-8 3 p.

Aurora- A and hBora join the game of polo

Macurek L., Lindqvist A., Medema R.H. 2009, In: Cancer Research. 69 , p. 4555-4558 4 p.

Polo-like kinase-1 controls Aurora A destruction by activating APC/C-Cdh1.

van Leuken R.J., Clijsters L., van Zon W., Lim D., Yao X., Wolthuis R.M.F., Yaffe M.B., Medema R.H., van Vugt M.A.T.M. 2009, In: PLoS ONE [E]. 4 , p. e5282 1 p.

No way out for tumor cells.

Rieder C.L., Medema R.H. 2009, In: Cancer Cell. 16 , p. 274-275 2 p.

Elevating the frequency of chromosome mis-segregation as a strategy to kill tumor cells

Janssen A., Kops G.J.P.L., Medema R.H. 2009, In: Proceedings of the National Academy of Sciences of the United States of America. 106 , p. 19108-19113 6 p.

Activation of FoxM1 during G2 requires CyclinA/Cdk-dependent relief of auto-repression by the FoxM1 N-terminal domain.

Laoukili J., Alvarez M., Meijer L.A.T., Stahl M., Mohammed S., Kleij L., Heck A.J.R., Medema R.H. 2008, In: Molecular and Cellular Biology. 28 , p. 3076-3087 12 p.

Dynein, Lis1 and CLIP-170 counteract Eg5-dependent centrosome separation during bipolar spindle assembly.

Tanenbaum M.E., Macurek L., Galjart N., Medema R.H. 2008, In: EMBO Journal. 27 , p. 3235-3245 11 p.

Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery.

Macurek L., Lindqvist A., Lim D., Lampson M.A., Klompmaker R., Freire R., Clouin C., Taylor S.S., Yaffe M.B., Medema R.H. 2008, In: Nature. 455 , p. 119-123 5 p.

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