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ir. R.S. Rosendaal

ir. R.S. Rosendaal

Full Professor

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Research Output (99)

Responsible use of organoids in precision medicine:The need for active participant involvement

Lensink Michael A., Jongsma Karin R., Boers Sarah N., Noordhoek Jacquelien J., Beekman Jeffrey M., Bredenoord Annelien L. Apr 2020, In: Development (Cambridge). 147

Intestinal organoids for Cystic Fibrosis research

de Poel E., Lefferts J. W., Beekman J. M. Mar 2020, In: Journal of Cystic Fibrosis. 19 Suppl 1 , p. S60-S64 5 p.

Activating alternative chloride channels to treat CF:Friends or Foes?: Report on the Meeting of the Basic Science Working Group in Dubrovnik, Croatia

Amaral Margarida D., Beekman Jeffrey M. 1 Jan 2020, In: Journal of Cystic Fibrosis. 19 , p. 11-15 5 p.

Lumacaftor/ivacaftor in people with cystic fibrosis with an A455E-CFTR mutation

Berkers Gitte, van der Meer Renske, Heijerman Harry, Beekman Jeffrey M, Boj Sylvia F, Vries Robert G J, van Mourik Peter, Doyle Jamie R, Audhya Paul, Yuan Zheng Jason, Kinnman Nils, van der Ent C Kors 2020, In: Journal of Cystic Fibrosis. 20 , p. 761-767 7 p.

Forskolin-induced swelling of intestinal organoids correlates with disease severity in adults with cystic fibrosis and homozygous F508del mutations

de Winter-de Groot Karin M, Berkers Gitte, Marck-van der Wilt Rozemarijn E P, van der Meer Renske, Vonk Annelotte, Dekkers Johanna F, Geerdink Margot, Michel Sabine, Kruisselbrink Evelien, Vries Rob, Clevers Hans, Vleggaar Frank P, Elias Sjoerd G, Heijerman Harry G M, van der Ent Cornelis K, Beekman Jeffrey M 14 Nov 2019, In: Journal of Cystic Fibrosis. 19 , p. 614-619 6 p.

Pharmacological analysis of CFTR variants of cystic fibrosis using stem cell-derived organoids

Chen Kevin G., Zhong Pingyu, Zheng Wei, Beekman Jeffrey M. 1 Nov 2019, In: Drug Discovery Today. 24 , p. 2126-2138 13 p.

A 'catch-and-release' receptor for the cholera toxin

Mahon Clare S., Wildsmith Gemma C., Haksar Diksha, De Poel Eyleen, Beekman Jeffrey M., Pieters Roland J., Webb Michael E., Turnbull W. Bruce 30 Oct 2019, In: Faraday discussions. 219 , p. 112-127 16 p.

High-resolution 3D imaging of fixed and cleared organoids

Dekkers Johanna F., Alieva Maria, Wellens Lianne M., Ariese Hendrikus C.R., Jamieson Paul R., Vonk Annelotte M., Amatngalim Gimano D., Hu Huili, Oost Koen C., Snippert Hugo J.G., Beekman Jeffrey M., Wehrens Ellen J., Visvader Jane E., Clevers Hans, Rios Anne C. 1 Jun 2019, In: Nature Protocols. 14 , p. 1756-1771 16 p.

In utero and postnatal VX-770 administration rescues multiorgan disease in a ferret model of cystic fibrosis

Sun Xingshen, Yi Yaling, Yan Ziying, Rosen Bradley H., Liang Bo, Winter Michael C., Evans T. Idil Apak, Rotti Pavana G., Yang Yu, Gray Jaimie S., Park Soo Yeun, Zhou Weihong, Zhang Yulong, Moll Shashanna R., Woody Lisa, Tran Dao M., Jiang Licong, Vonk Annelotte M., Beekman Jeffrey M., Negulescu Paul, Van Goor Fred, Fiorino Dennis F., Gibson-Corley Katherine N., Engelhardt John F. 27 Mar 2019, In: Science Translational Medicine. 11

FcγRIII stimulation breaks the tolerance of human nasal epithelial cells to bacteria through cross-talk with TLR4

Golebski K., Hoepel W., van Egmond D., de Groot E. J., Amatngalim G. D., Beekman J. M., Fokkens W. J., van Drunen C. M., den Dunnen J. 1 Mar 2019, In: Mucosal immunology. 12 , p. 425-433 9 p.

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