ir. drs. N.O. (Daniel) Quaedvlieg

ir. drs. N.O. (Daniel) Quaedvlieg

Assistant Professor - medical
ir. drs. N.O. (Daniel) Quaedvlieg
  • Birth Center Neonatology - Medical

Research Programs

Child Health



After finishing high school, Daniel Vijlbrief (1975) studied at Millersville University of Pennsylvania through the Fulbright scholarship program. Returning in the Netherlands, he studied Medicine at Utrecht University. He specialized in Pediatrics in Utrecht and Tilburg and continued in Neonatology in the Wilhelmina children’s hospital in Utrecht and the Isala clinics in Zwolle. He works as a consultant neonatologist in Utrecht. In 2015, he finished his Ph.D. in medicine with the title ‘Cardiac Biomarkers in neonatology’. Currently, he is investigating the possibilities of Big Data in neonatal medicine, in the Big Data for Small Babies project. First investigations are ongoing in the applied data analytic in medicine (ADAM) project. This project aims to build an early warning system and decision support tool for late-onset neonatal sepsis. Future research will be directed to bringing algorithms to clinical care in newborn medicine.   

Research Output (43)

Multi-centre, randomised non-inferiority trial of early treatment versus expectant management of patent ductus arteriosus in preterm infants (the BeNeDuctus trial):statistical analysis plan

Hundscheid Tim, Donders Rogier, Onland Wes, Kooi Elisabeth M.W., Vijlbrief Daniel C., de Vries Willem B., Nuytemans Debbie H.G.M., van Overmeire Bart, Mulder Antonius L., de Boode Willem P., Dijk Peter H., van Kaam Anton H.L.C., de Baat Tessa, Dijkman Koen P., Villamor Eduardo, Kroon André A., Visser Remco, de Tollenaer Susanne M., Cools Filip, Meeus Marisse, Johansson Anne Britt, Derriks Frank, Hocq Catheline, Zecic Alexandra, Henriksen Tine Brink, Kyng Kasper Jacobsen, Dec 2021, In: Trials. 22

Development of an automated real-time sleep-state prediction algorithm in preterm infants: the Sleep Well Baby project

Sentner Thom, van Schaijk Lieke, de Groot Eline, Wang Xiaowan, Bartels Richard, Vijlbrief Daniel, Benders Manon, Dudink Jeroen Oct 2021, p. 9-9

Expectative management of a patent ductus arteriosus: pays the brain the price?

Vijlbrief D, van Bel Frank, Lemmers PM, Alderliesten Thomas, Benders M, Baerts Wim 15 Sep 2021,

Precision Medicine in Neonates:A Tailored Approach to Neonatal Brain Injury

Tataranno Maria Luisa, Vijlbrief Daniel C, Dudink Jeroen, Benders Manon J N L 19 May 2021, In: Frontiers in Pediatrics. 9 , p. 1-13


Vijlbrief D, Frerichs Nina, Niemarkt Hendrik J, de Boode Willem P, 1 May 2021,

Isoprostanes as Biomarker for White Matter Injury in Extremely Preterm Infants

Coviello Caterina, Perrone Serafina, Buonocore Giuseppe, Negro Simona, Longini Mariangela, Dani Carlo, de Vries Linda S, Groenendaal Floris, Vijlbrief Daniel C, Benders Manon J N L, Tataranno Maria Luisa 15 Jan 2021, In: Frontiers in Pediatrics. 8

Dalteparin in Newborn Thrombosis, Time for a New Starting Dose

Steenman Frouwke, Vijlbrief Daniel C, Huisman Albert, Bierings Marc 2021, In: Neonatology. 118 , p. 345-347 3 p.

NEOCLOT: Management of Catheter-related Venous Thrombosis in Preterm and Term Neonates [abstract].

Vijlbrief D, van Ommen C. Heleen, Bergman Klasien A, Boerma Marit, Gouvernante , Hulzebos Christiaan V, Kahndour D, Knol Ronny, 2021,

Preclinical Detection of Non-catheter Related Late-onset Sepsis in Preterm Infants by Fecal Volatile Compounds Analysis:A Prospective, Multi-center Cohort Study

Berkhout Daniel J C, Niemarkt Hendrik J, Andriessen Peter, Vijlbrief Daniel C, Bomers Marije K, Cossey Veerle, Hulzebos Christian V, van Kaam Anton H, Kramer Boris W, van Lingen Richard A, Wicaksono Alfian N, Covington James A, van Weissenbruch Mirjam M, Benninga Marc A, de Boer Nanne K H, de Meij Tim G J 1 Apr 2020, In: The Pediatric infectious disease journal. 39 , p. 330-335 6 p.

The development and validation of a cerebral ultrasound scoring system for infants with hypoxic-ischaemic encephalopathy

Annink Kim V, de Vries Linda S, Groenendaal Floris, Vijlbrief Daniel C, Weeke Lauren C, Roehr Charles C, Lequin Maarten, Reiss Irwin K M, Govaert Paul, Benders Manon J N L, Dudink Jeroen Mar 2020, In: Pediatric Research. 87 , p. 59-66 8 p.

All research output

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