drs. ing. A.B. (Bas W.) Leendertse
drs. ing. A.B. (Bas W.) Leendertse
- Experimental Clinical Physics Radiotherapy
Research Programs
Biography
Biography
Bas Raaymakers is working to improve cancer therapy by investigating, as well as developing, new high precision radiotherapy.
Together with prof Jan Lagendijk but also with industrial partners Elekta and Philips he designed and built a hybrid MRI accelerator to facilitate high precision, soft-tissue based image guidance for radiotherapy. This enables better radiotherapy via dose escalation while decreasing toxicity.
At the same time, the translation of this new technology to the clinic is pursued. For instance fast, on-line treatment planning, so that the patient is treated based on the latest state of the anatomy. This improves the current radiotherapy practice and at the same time is a requirement for smooth clinical introduction of the MRI accelerator.
Clinical work flow and procedures for different tumour sites are under investigation. Two major categories can be distinguished: The first is improving the existing radiotherapy patient treatments, so better conform the dose distribution to the tumour shape to minimise harm to the surroundings. The second is enabling radiotherapy as an alternative for surgery for patients currently not eligible for radiotherapy, e.g. highly mobile tumours in the kidney. The motion is too large to safely administer dose with conventional radiotherapy technology, with the on-line MRI guidance the motion uncertainty can be mitigated and radiation can be safely administered, offering a completely non-invasive treatment.
Side Activities
Member of International Advisory Committee of Physics in Medicine and Biology (unpaid)
Fellowship and Awards
VENI grant in 2003, Technical feasibility of the MRI accelerator
Research Output (200)
Lagendijk Jan J W, Raaymakers Bas W, Intven Martijn P W, van der Voort van Zyp Jochem R N Nov 2022, In: Radiotherapy & Oncology. 176 , p. 244-248 5 p.
Tsekas Georgios, Bol Gijsbert H, Raaymakers Bas W 5 Oct 2022, In: Physics in medicine and biology. 67
Willigenburg Thomas, Zachiu Cornel, Bol Gijsbert H, de Groot-van Beugel Eline N, Lagendijk Jan J W, van der Voort van Zyp Jochem R N, Raaymakers Bas W, de Boer Johannes C J 14 Sep 2022, In: Radiotherapy & Oncology. 176 , p. 25-30 6 p.
Akdag Osman, Borman Pim T S, Woodhead Peter L, Uijtewaal Prescilla, Mandija Stefano, van Asselen Bram, Verhoeff Joost J C, Raaymakers Bas W, Fast Martin F 21 Feb 2022, In: Physics in medicine and biology. 67 , p. 1-14
Akdag Osman, Mandija Stefano, van Lier Astrid L H M W, Borman PTS, Schakel Tim, Alberts Eveline, van der Heide Oscar, Hassink Rutger J, Verhoeff Joost J C, Mohamed Hoesein Firdaus A A, Raaymakers Bas W, Fast Martin F Jan 2022, In: Physics and Imaging in Radiation Oncology. 21 , p. 153-159 7 p.
Willigenburg Thomas, Zachiu Cornel, Lagendijk Jan J W, van der Voort van Zyp Jochem R N, de Boer Hans C J, Raaymakers Bas W Jan 2022, In: Physics and Imaging in Radiation Oncology. 21 , p. 62-65 4 p.
Grimbergen Guus, Eijkelenkamp Hidde, Heerkens Hanne D., Raaymakers Bas W., Intven Martijn P.W., Meijer Gert J. Jan 2022, In: Physics and Imaging in Radiation Oncology. 21 , p. 1-5 5 p.
Guerreiro F., Svensson S., Seravalli E., Traneus E., Raaymakers B. W. 21 Sep 2021, In: Physics in medicine and biology. 66 9 p.
De D. M. Muinck Keizer, Willigenburg T., Van J. R. N. der Voort van Zyp, Raaymakers B. W., Lagendijk J. J. W., De J. C. J. Boer Sep 2021, In: Radiotherapy and Oncology. 162 , p. 162-169 8 p.
Grimbergen G., Eijkelenkamp H., Heerkens H., Raaymakers B., Intven M., Meijer G. Aug 2021, In: Radiotherapy and Oncology. 161 , p. S695-S697