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mr. drs. X.Y.Y. (Monique) Koot

mr. drs. X.Y.Y. (Monique) Koot

Associate Professor

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Research Output (121)

HIV-1 remission following CCR5Δ32/Δ32 haematopoietic stem-cell transplantation

Gupta Ravindra K., Abdul-Jawad Sultan, McCoy Laura E., Mok Hoi Ping, Peppa Dimitra, Salgado Maria, Martinez-Picado Javier, Nijhuis Monique, Wensing Annemarie M.J., Lee Helen, Grant Paul, Nastouli Eleni, Lambert Jonathan, Pace Matthew, Salasc Fanny, Monit Christopher, Innes Andrew J., Muir Luke, Waters Laura, Frater John, Lever Andrew M.L., Edwards Simon G., Gabriel Ian H., Olavarria Eduardo 11 Apr 2019, In: Nature. 568 , p. 244-248 5 p.

Rapid Rebound of a Preexisting CXCR4-tropic Human Immunodeficiency Virus Variant After Allogeneic Transplantation With CCR5 Δ32 Homozygous Stem Cells

Verheyen Jens, Thielen Alexander, Lübke Nadine, Dirks Miriam, Widera Marek, Dittmer Ulf, Kordelas Lambros, Däumer Martin, De Jong Dorien C.M., Wensing Annemarie M.J., Kaiser Rolf, Nijhuis Monique, Esser Stefan 15 Feb 2019, In: Clinical Infectious Diseases. 68 , p. 684-687 4 p.

All-printed cell counting chambers with on-chip sample preparation for point-of-care CD4 counting

Wasserberg Dorothee, Zhang Xichen, Breukers Christian, Connell Bridgette J., Baeten Ellen, van den Blink Dorine, Solà Benet Èlia, Bloem Andries C., Nijhuis Monique, Wensing Annemarie M.J., Terstappen Leon W.M.M., Beck Markus 15 Oct 2018, In: Biosensors and Bioelectronics. 117 , p. 659-668 10 p.

Development of sensitive ddPCR assays to reliably quantify the proviral DNA reservoir in all common circulating HIV subtypes and recombinant forms

Bosman Kobus J., Wensing Annemarie M. J., Pijning Aster E., van Snippenberg Wilco J., van Ham Petra M., de Jong Dorien M. C., Hoepelman Andy I. M., Nijhuis Monique 14 Sep 2018, In: Journal of the International AIDS Society [E]. 21

The antiretroviral CCR5-inhibitor maraviroc effectively reverses HIV latency by phosphorylation of Nf-kappa B

Symons J., vanLelyveld S. F. L., deSpiegelaere W., Wensing A. M. J., Zerbato J. M., vanHam P. M., Drylewicz J., Middel A., Hoepelman A. I. M., Cameron P. U., Lu H. K., Dantanarayana A. I., Borghans J. A. M., Vandekerckhove L., Lewin S. R., Tesselaar K., Nijhuis M. Jul 2018, In: Journal of the International AIDS Society [E]. 21 , p. 29-30

Impact of the HIV-1 genetic background and HIV-1 population size on the evolution of raltegravir resistance

Fun Axel, Leitner Thomas, Vandekerckhove Linos, Däumer Martin, Thielen Alexander, Buchholz Bernd, Hoepelman Andy I.M., Gisolf Elizabeth H., Schipper Pauline J., Wensing Annemarie M.J., Nijhuis Monique 5 Jan 2018, In: Retrovirology. 15 13 p.

A combinational CRISPR/Cas9 gene-editing approach can halt HIV replication and prevent viral escape

Lebbink Robert Jan, de Jong Dorien C M, Wolters Femke, Kruse Elisabeth M, van Ham Petra M, Wiertz Emmanuel J H J, Nijhuis Monique 8 Feb 2017, In: Scientific Reports. 7

HIV protease inhibitor resistance

Wensing Annemarie M.J., Fun Axel, Nijhuis Monique 1 Jan 2017, p. 567-602 36 p.

High rates of transmission of drug-resistant HIV in Aruba resulting in reduced susceptibility to the WHO recommended first-line regimen in nearly half of newly diagnosed HIV-infected patients

Hofstra L. Marije, Rivas Elena Sánchez, Nijhuis Monique, Bank Leonie E.A., Wilkinson Eduan, Kelly Karina, Mudrikova Tania, Schuurman Rob, De Oliveira Tulio, De Kort Jaclyn, Wensing Annemarie M.J. 2017, In: Clinical Infectious Diseases. 64 , p. 1092-1097 6 p.

CRISPR/Cas9-Mediated Genome Editing of Herpesviruses Limits Productive and Latent Infections

van Diemen Ferdy R., Kruse Elisabeth M., Hooykaas Marjolein J G, Bruggeling Carlijn E., Schürch Anita C., van Ham Petra M., Imhof Saskia M., Nijhuis Monique, Wiertz Emmanuel J H J, Lebbink Robert Jan 1 Jun 2016, In: PLoS Pathogens. 12

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