prof. dr. D. (Kees) Hilderink
prof. dr. D. (Kees) Hilderink
- Neurologen
Research Programs
Biography
Biography
Kees Braun obtained his Medical Degree at Utrecht University in January 1992. He specialized in Neurology (registered in 2000) and Paediatric Neurology (registered in 2002) in the UMC Utrecht. In 2000 he obtained his PhD degree on a thesis entitled “Magnetic Resonance Spectroscopy in Hydrocephalus. He was appointed as staff neurologist in 2000 and paediatric neurologist in 2002. Since 2011 he is head of Paediatric Neurology/Neurosurgery. In May 2012 he was appointed as a full professor of Paediatric Neurology.
His clinical and scientific areas of expertise are: refractory paediatric epilepsy, epilepsy surgery, imaging in epilepsy, and childhood arteriopathic stroke, in particular moyamoya treatment.
He coordinates epilepsy research in the UMCU Brain center. The epilepsy research projects he is personally involved in focus on the effects of focal epilepsy on the brain in animal models and patients (structural and functional integrity and network analysis); seizure- and cognitive outcome after paediatric epilepsy surgery; postoperative antiepileptic drug withdrawal; ESES treatment; stress and epilepsy; and epileptic focus detection in surgical candidates.
Kees Braun currently is president of the Dutch Society of Paediatric Neurology and of the organizing committee of the 2016 world congress of child neurology (ICNC) in Amsterdam. He is member of the European Task Force for Epilepsy Surgery in Children (U-Task), the European Network for Epilepsy Research (ENER), and work-package leader of the EU-funded E-PILEPSY project.
Research line
Refractory epilepsy
Most recent key publications
1: Boshuisen K, Arzimanoglou A, Cross JH, Uiterwaal CS, Polster T, van Nieuwenhuizen O, Braun KP; for the TimeToStop study Group. Timing of antiepileptic drug withdrawal and long-term seizure outcome after paediatric epilepsy surgery (TimeToStop): a retrospective observational study. Lancet Neurol 2012:11:784-791
2: Van Campen JS, Jansen FE, Pet MA, Otte WM, Hillegers MH, Joels M, Braun KP. Relation between stress-precipitated seizures and the stress response in childhood epilepsy. Brain 2015;138:2234-2248
3: Lamberink HJ, Boshuisen K, van Rijen PC, Gosselaar PH, Braun KP. Changing profiles of pediatric epilepsy surgery candidates over time: a nationwide single-center experience from 1990 to 2011. Epilepsia 215;56:717-725
4: Boshuisen K, van Schooneveld MM, Uiterwaal CS, Cross JH, Harrison S, Polster T, Daehn M, Djimjadi S, Yalnizoglu D, Turanli G, Sassen R, Hoppe C, Kuczaty S, Barba C, Kahane P, Schubert-Bast S, Reuner G, Bast T, Strobl K, Mayer H, de Saint-Martin A, Seegmuller C, Laurent A, Arzimanoglou A, Braun KP, for the TimeToStop cognitive outcome study group. Intelligence quotient improves after antiepileptic drug withdrawal following pediatric epilepsy surgery. Ann Neurol 2015;78:104-114
5: Braun KPJ, Bulder MMM, Chabrier S, Kirkham FJ, Uiterwaal CSP, Tardieu M, Sebire G. Longitudinal vascular imaging in 79 children with ischemic stroke and unilateral intracranial arteriopathy. Brain 2009;132:544-557
Side Activities
As mentioned in the Biography.
Fellowship and Awards
1: Recipient of the first “Patrick Hanlo Award”, March 17 2009
2: Personal investment grant for epilepsy research by the Dutch National Epilepsy Fund
3: Recipient of the “Gerlach Cerfontaine Fellowship” of the Catharijne Foundation, UMCU, 1998-2000, for the PhD project “Magnetic Resonance Spectroscopy in Hydrocephalus”
4: Recipient of several research grants from e.g. the Dutch Epilepsy Fund, Johanna Children’s Fund, and Wilhelmina Research Fund.
Research Output (256)
Stevering Carmen H., Lamberink Herm J., Woodfield Julie, van Schooneveld Monique, Otte Willem M., Chin Richard F.M., Bastin Mark E., Geleijns Karin, Braun Kees P.J. 1 Oct 2022, In: Epileptic disorders : international epilepsy journal with videotape. 24 , p. 877-888 12 p.
Hulshof Hanna M, Kuijf Hugo J, Kotulska Katarzyna, Curatolo Paolo, Weschke Bernhard, Riney Kate, Krsek Pavel, Feucht Martha, Nabbout Rima, Lagae Lieven, Jansen Anna, Otte Wim M, Lequin Maarten H, Sijko Kamil, Benvenuto Arianna, Hertzberg Christoph, Benova Barbora, Scholl Theresa, De Ridder Jessie, Aronica EleonoraM A, Kwiatkowski David J, Jozwiak Sergiusz, Jurkiewicz Elzbieta, Braun Kees, Jansen Floor E, 31 Jan 2022, In: Neurology. 98 , p. e1216-e1225
Noorlag Lotte, van Klink Nicole E.C., Kobayashi Katsuhiro, Gotman Jean, Braun Kees P.J., Zijlmans Maeike 20 Jan 2022, In: Clinical Neurophysiology. 137 , p. 46-58 13 p.
Cloppenborg Thomas, van Schooneveld Monique, Hagemann Anne, Hopf Johanna Lena, Kalbhenn Thilo, Otte Willem M., Polster Tilman, Bien Christian G., Braun Kees P.J. 18 Jan 2022, In: Neurology. 98 , p. e225-e235
Terman Samuel W., Lamberink Herm J., Slinger Geertruida, Otte Willem M., Burke James F., Braun Kees P.J. Dec 2021, In: Epilepsia. 62 , p. 3146-3147 2 p.
Hulshof Hanna M., Benova Barbora, Krsek Pavel, Kyncl Martin, Lequin Maarten H., Belohlavkova Anezka, Jezdik Petr, Braun Kees P.J., Jansen Floor E. Dec 2021, In: Epilepsia Open. 6 , p. 663-671 9 p.
Jehi Lara, Morita-Sherman Marcia, Love Thomas E., Bartolomei Fabrice, Bingaman William, Braun Kees, Busch Robyn M., Duncan John, Hader Walter J., Luan Guoming, Rolston John D., Schuele Stephan, Tassi Laura, Vadera Sumeet, Sheikh Shehryar, Najm Imad, Arain Amir, Bingaman Justin, Diehl Beate, de Tisi Jane, Rados Matea, Van Eijsden Pieter, Wahby Sandra, Wang Xiongfei, Wiebe Samuel Dec 2021, In: Annals of Neurology. 90 , p. 927-939 13 p.
Slinger Geertruida, Otte Willem M, Braun Kees P J, van Diessen Eric 20 Nov 2021, In: Neuroscience and Biobehavioral Reviews. 132 , p. 211-223 13 p.
Noorlag Lotte, van 't Klooster Maryse, van Huffelen Alexander, van Klink Nicole, Benders Manon, de Vries Linda, Leijten Frans, Jansen Floor E., Braun Kees, Zijlmans Maeike Nov 2021, In: Epilepsia. 62 , p. 114-115
Mouthaan Brian E., Jansen Floor E., Colon Albert J., Huiskamp Geertjan M., van Eijsden Pieter, Leijten Frans S.S., Braun Kees P.J. 29 Oct 2021, In: Clinical Neurophysiology. 133 , p. 126-134 9 p.