prof.dr. V.W. (Jan C.) Heerdink

prof.dr. V.W. (Jan C.) Heerdink

Full Professor
prof.dr. V.W. (Jan C.) Heerdink
  • Department of Pulmonary Diseases

Research Programs

Infection & Immunity



Jan C. Grutters (1966) studied Medicine at the University of Nijmegen, and was trained in Respiratory Medicine at St. Antonius Hospital Nieuwegein and University Medical Center (UMC) Utrecht, the Netherlands. In 2001 he was awarded an ERS Research Fellowship at the Imperial College and Royal Brompton Hospital London, resulting in the Thesis: ‘Genetic polymorphisms and phenotypes in sarcoidosis’. Since 2002 he works as chest physician at St. Antonius Hospital, where he is head of the Interstitial Long Diseases (ILD)  Center of Excellence (currently treating >3000 ILD patients/yr), and UMC Utrecht, where he is member of the Lung Transplant Team. From 2009 to 2011 he was head of training Pulmonology & Tuberculosis at St. Antonius Hospital. In 2010 he was appointed Professor of ILD at University Utrecht. His research focuses on genetics, biomarkers and novel therapies for lung fibrosis, sarcoidosis and ultra-rare ILD such as lymphangioleiomyomatosis and pulmonary alveolar proteinosis. Jan Grutters has been/is supervisor of >40 PhD students, published over 250 papers in international scientific journals and books, and is regularly invited as speaker and/or chairman at national and international medical/scientific congresses, seminars and meetings.

Side Activities

chairman Sectie ILD (SIL) NVALT
chairman Prof. Dr. Jaap Swierenga Stichting
vice president World Association of Sarcoidosis and Other Granulomatous Disorders (WASOG)
chief medical advisor European Sarcoidosis Foundation
member wetenschappelijke adviesraad (WAR) St Antonius  Onderzoeksfonds
member wetenschappelijke adviescommissie (WAC) Longfonds
member Horizonscan geneesmiddelen ZiN
member commissie dure geneesmiddelen NVALT
member commissie immuunglob COVID-19 ZonMw
member medische adviesraad
member medische adviesraad Longfibrose patientenvereniging
member medische adviesraad Nationale Vereniging Sjogrenpatienten
medisch adviseur stichting LAM-Nederland
member Editorial Board of the journal SVDLD
member forum CPMS ERN-LUNG
member Nederlands asbestosis panel IAS 
member Data Monitoring Committee BI trial 1305-0013 (parexel)
member Adjudication Committee Pliant (Pliant)
member Steering Comittee Sphinx trial (Actelion)


Research Output (228)

ANXA11 rs1049550 Associates with Löfgren's Syndrome and Chronic Sarcoidosis Patients

Karakaya Bekir, van der Vis Joanne J, Veltkamp Marcel, Biesma Douwe H, Grutters Jan C, van Moorsel Coline H M 1 May 2022, In: Cells. 11 , p. 1-11

ANXA11 rs1049550 Associates with Löfgren’s Syndrome and Chronic Sarcoidosis Patients

Karakaya Bekir, van der Vis Joanne J., Veltkamp Marcel, Biesma Douwe H., Grutters Jan C., van Moorsel Coline H.M. 1 May 2022, In: Cells. 11

Clustering of lung diseases in the family of interstitial lung disease patients

Terwiel Michelle, Grutters Jan C, van Moorsel Coline H M 7 Apr 2022, In: BMC Pulmonary Medicine. 22 , p. 1-10

WASOG statement on the diagnosis and management of sarcoidosis-associated pulmonary hypertension

Savale Laurent, Huitema Marloes, Shlobin Oksana, Kouranos Vasilis, Nathan Steven D, Nunes Hiliaro, Gupta Rohit, Grutters Jan C, Culver Daniel A, Post Marco C, Ouellette Daniel, Lower Elyse E, Al-Hakim Tamara, Wells Athol U, Humbert Marc, Baughman Robert P 31 Mar 2022, In: European Respiratory Review. 31 , p. 1-17

The detrimental effect of quantity of smoking on survival in progressive fibrosing ILD

Platenburg M. G.J.P., van der Vis J. J., Kazemier K. M., Grutters J. C., van Moorsel C. H.M. 5 Feb 2022, In: Respiratory Medicine. 194 , p. 1-8

Neutrophil count, lymphocyte count and neutrophil-to-lymphocyte ratio in relation to response to adjunctive dexamethasone treatment in community-acquired pneumonia

Wittermans Esther, van de Garde Ewoudt MW, Voorn G. Paul, Aldenkamp Arnoud F., Janssen Rob, Grutters Jan C., Bos Willem Jan W., Feb 2022, In: European journal of internal medicine. 96 , p. 102-108 7 p.

Potential therapeutic targets to prevent organ damage in chronic pulmonary sarcoidosis

Nienhuis Wa, Grutters Jc 21 Jan 2022, In: Expert opinion on therapeutic targets. 26 , p. 41-55 15 p.

The use of online visual analogue scales in idiopathic pulmonary fibrosis

Moor Catharina C., Mostard Remy L.M., Grutters Jan C., Bresser Paul, Wijsenbeek Marlies S. 1 Jan 2022, In: European Respiratory Journal. 59 , p. 1-4

Echocardiographic estimate of pulmonary artery pressure in sarcoidosis patients - real world data from a multi-national study

Huitema Marloes P, Post Marco C, Grutters Jan C, Wells Athol U, Kouranos Vasilis, Shlobin Oksana A, Nathan Steven D, Culver Daniel A, Barney Joseph, Gupta Rohit, Carmona Eva, Alhamad Esam H, Scholand Mary B, Wijsenbeek Marlies, Ganesh Sivagini, Lower Elyse E, Engel Peter J, Baughman Robert P 2022, In: Sarcoidosis, Vasculitis, and Diffuse Lung Diseases. 38 , p. e2021032

Community-acquired pneumonia subgroups and differential response to corticosteroids: a secondary analysis of controlled studies

Wittermans Esther, van der Zee Philip A., Qi Hongchao, van de Garde Ewoudt M. W., Blum Claudine A., Christ-Crain Mirjam, Gommers Diederik, Grutters Jan C., Voorn G. Paul, Bos Willem Jan W., Endeman Henrik 2022, In: ERJ Open Research. 8 , p. 1-11

All research output

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