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dr. R.S. (Coen) Groenendal

dr. R.S. (Coen) Groenendal

Associate Professor
dr. R.S. (Coen) Groenendal
  • Central Diagnostic Laboratory

Research Programs

Circulatory Health

Research Output (87)

VhH anti-thrombomodulin clone 1 inhibits TAFI activation and enhances fibrinolysis in human whole blood under flow

van Moorsel Marc V A, Poolen Geke, Koekman Cornelis A, Verhoef Sandra, de Maat Steven, Barendrecht Arjan, van Kleef Nadine D, Meijers Joost C M, Schiffelers Raymond, Maas Coen, Urbanus Rolf T 16 Feb 2022, In: Journal of thrombosis and haemostasis : JTH. 20 , p. 1213-1222 10 p.

Serum proteases prevent bacterial biofilm formation:role of kallikrein and plasmin

Arenas Jesús, Szabo Zalan, van der Wal Jelle, Maas Coen, Riaz Tahira, Tønjum Tone, Tommassen Jan Dec 2021, In: Virulence. 12 , p. 2902-2917 16 p.

A reactive center loop-based prediction platform to enhance the design of therapeutic SERPINs

Sanrattana Wariya, Sefiane Thibaud, Smits Simone, van Kleef Nadine D, Fens Marcel H, Lenting Peter J, Maas Coen, de Maat Steven 9 Nov 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118

Microlyse; a thrombolytic agent that targets VWF for clearance of microvascular thrombosis

de Maat Steven, Clark Chantal, Barendrecht Arjan D, Smits Simone, van Kleef Nadine D, El Otmani Hinde, Waning Manon, van Moorsel Marc Vincent Adriaan, Szardenings Michael, Delaroque Nicolas, Vercruysse Kristof, Urbanus Rolf T, Sebastian Silvie, Lenting Peter J, Hagemeyer Christoph Eugen, Renné Thomas, Vanhoorelbeke Karen, Tersteeg Claudia, Maas Coen 9 Nov 2021, In: Blood. 139 , p. 597-607 11 p.

Illustrated State-of-the-Art Capsules of the ISTH 2021 Congress

Krishnaswamy Sriram, Ageno Walter, Arabi Yaseen, Barbui Tiziano, Cannegieter Suzanne, Carrier Marc, Cleuren Audrey C, Collins Peter, Panicot-Dubois Laurence, Freedman Jane E, Freson Kathleen, Hogg Philip, James Andra H, Kretz Colin A, Lavin Michelle, Leebeek Frank W G, Li Weikai, Maas Coen, Machlus Kellie, Makris Michael, Martinelli Ida, Medved Leonid, Neerman-Arbez Marguerite, O'Donnell James S, O'Sullivan Jamie, Rajpurkar Madhvi, Schroeder Verena, Spiegel Paul Clinton, Stanworth Simon J, Green Laura, Undas Anetta Jul 2021, In: Research and practice in thrombosis and haemostasis. 5 , p. 1-34

Blood Clotting and the Pathogenesis of Types I and II Hereditary Angioedema

de Maat Steven, Joseph Kusumam, Maas Coen, Kaplan Allen P Jun 2021, In: Clinical Reviews in Allergy & Immunology. 60 , p. 348-356 9 p.

Defective NET clearance contributes to sustained FXII activation in COVID-19-associated pulmonary thrombo-inflammation

Englert Hanna, Rangaswamy Chandini, Deppermann Carsten, Sperhake Jan-Peter, Krisp Christoph, Schreier Danny, Gordon Emma, Konrath Sandra, Haddad Munif, Pula Giordano, Mailer Reiner K, Schlüter Hartmut, Kluge Stefan, Langer Florian, Püschel Klaus, Panousis Kosta, Stavrou Evi X, Maas Coen, Renné Thomas, Frye Maike May 2021, In: EBioMedicine. 67 , p. 1-9

Dysregulated Innate and Adaptive Immune Responses Discriminate Disease Severity in COVID-19

Janssen Nico A.F., Grondman Inge, de Nooijer Aline H., Boahen Collins K., Koeken Valerie A.C.M., Matzaraki Vasiliki, Kumar Vinod, He Xuehui, Kox Matthijs, Koenen Hans J.P.M., Smeets Ruben L., Joosten Irma, Brüggemann Roger J.M., Kouijzer Ilse J.E., van der Hoeven Hans G., Schouten Jeroen A., Frenzel Tim, Reijers Monique H.E., Hoefsloot Wouter, Dofferhoff Anton S.M., van Apeldoorn Marjan J., Blaauw Marc J.T., Veerman Karin, Maas Coen, Schoneveld Arjan H., Hoefer Imo E., Derde Lennie P.G., van Deuren Marcel, van der Meer Jos W.M., van Crevel Reinout, Giamarellos-Bourboulis Evangelos J., Joosten Leo A.B., van den Heuvel Michel M., Hoogerwerf Jacobien, de Mast Quirijn, Pickkers Peter, Netea Mihai G., van de Veerdonk Frank L. 23 Apr 2021, In: The Journal of infectious diseases. 223 , p. 1322-1333 12 p.

Thrombotic Events in COVID-19 Are Associated With a Lower Use of Prophylactic Anticoagulation Before Hospitalization and Followed by Decreases in Platelet Reactivity

Clark Chantal C., Jukema Bernard N., Barendrecht Arjan D., Spanjaard Judith S., Jorritsma Nikita K.N., Smits Simone, de Maat Steven, Seinen Cor W., Verhoef Sandra, Parr Naomi M.J., Sebastian Silvie A.E., Koekman Arnold C., van Wesel Annet C.W., van Goor Harriet M.R., Spijkerman Roy, Bongers Suzanne H., van der Vries Erhard, Nierkens Stefan, Boes Marianne, Koenderman Leo, Kaasjager Karin A.H., Maas Coen, 22 Apr 2021, In: Frontiers in medicine. 8 , p. 1-11

Therapeutic SERPINs:Improving on Nature

Maas Coen, de Maat Steven 31 Mar 2021, In: Frontiers in cardiovascular medicine. 8 , p. 1-8

All research output

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