dr. ir. O.P.P. (Julia) Geurds

dr. ir. O.P.P. (Julia) Geurds

Assistant Professor
dr. ir. O.P.P. (Julia) Geurds
  • Center for Translational Immunology (CTI) Computational Immunology Core

Research Programs

Infection & Immunity



Julia Drylewicz is an Assistant Professor within the Computational Immunology Core of the Center for Translational Immunology (CTI) of the UMC Utrecht focusing on biomarkers discovery and bringing methodological support to researchers from the design of a project to its publication.

Since 2014, she collaborates with many groups on multidisciplinary projects within the CTI and aim at closing the gap between experimental and theoretical work by using biostatistics, bioinformatics and computational approaches. Some of her most recent projects involve modeling cell homeostasis in human, defining the optimal time of maternal vaccination for RSV infection, determining endotypes of atopic dermatitis patients based on serum biomarkers measured by Luminex and analyses of Olink data.  

She was trained in Biostatistics and Epidemiology at Bordeaux School of Public Health (ISPED, France) and graduated in Biomathematics from Paris V University (France) in 2006. She obtained her PhD in biostatistics at Bordeaux University (France) in 2009. From 2010 till 2014, she performed postdoctoral research in computational and quantitative immunology under the supervision of José Borghans in the Department of Immunology at the UMC Utrecht and collaborated with Rob de Boer in the Utrecht Center for Quantitative Immunology at Utrecht University. Her research focused on quantifying cell dynamics in health and disease using mathematical modeling to analyze stable-isotope labeling experiments.

Research Output (51)

Quantification of T-cell dynamics during latent cytomegalovirus infection in humans

van den Berg Sara P.H., Derksen Lyanne Y., Drylewicz Julia, Nanlohy Nening M., Beckers Lisa, Lanfermeijer Josien, Gessel Stephanie N., Vos Martijn, Otto Sigrid A., de Boer Rob J., Tesselaar Kiki, Borghans José A.M., van Baarle Debbie Dec 2021, In: PLoS Pathogens. 17

T-Cell Epitopes Shared Between Immunizing HLA and Donor HLA Associate With Graft Failure After Kidney Transplantation

Peereboom Emma T M, Matern Benedict M, Tomosugi Toshihide, Niemann Matthias, Drylewicz Julia, Joosten Irma, Allebes Wil A, van der Meer Arnold, Hilbrands Luuk B, Baas Marije C, van Reekum Franka E, Verhaar Marianne C, Kamburova Elena G, Seelen Marc A J, Sanders Jan Stephan, Hepkema Bouke G, Lambeck Annechien J, Bungener Laura B, Roozendaal Caroline, Tilanus Marcel G J, Voorter Christien E, Wieten Lotte, van Duijnhoven Elly M, Gelens Mariëlle A C J, Christiaans Maarten H L, van Ittersum Frans J, Nurmohamed Azam, Lardy Neubury M, Swelsen Wendy, van der Pant Karlijn A, van der Weerd Neelke C, Ten Berge Ineke J M, Bemelman Fréderike J, de Vries Aiko P J, de Fijter Johan W, Betjes Michiel G H, Roelen Dave L, Claas Frans H, Otten Henny G, Heidt Sebastiaan, van Zuilen Arjan D, Kobayashi Takaaki, Geneugelijk Kirsten, Spierings Eric 18 Nov 2021, In: Frontiers in Immunology. 12 , p. 1-13

Serum Biomarker Profile Including CCL1, CXCL10, VEGF, and Adenosine Deaminase Activity Distinguishes Active From Remotely Acquired Latent Tuberculosis

Delemarre Eveline M, van Hoorn Laura, Bossink Aik W J, Drylewicz Julia, Joosten Simone A, Ottenhoff Tom H M, Akkerman Onno W, Goletti Delia, Petruccioli Elisa, Navarra Assunta, van den Broek Brigitte T A, Paardekooper Sanne P A, van Haeften Ineke, Koenderman Leo, Lammers Jan-Willem J, Thijsen Steven F T, Hofland Regina W, Nierkens Stefan 7 Oct 2021, In: Frontiers in Immunology. 12 , p. 1-12

Unraveling heterogeneity in pediatric atopic dermatitis::identification of serum biomarker based patient clusters

Bakker D., de Graaf M., Nierkens S., Delemarre E., Knol E., van Wijk F., de Bruin-Weller M., Drylewicz J., Thijs J. Oct 2021, In: Journal of Investigative Dermatology. 141 , p. S189-S189

Long-term effect of hematopoietic cell transplantation on systemic inflammation in patients with mucopolysaccharidoses

van den Broek Brigitte T A, Lindemans Caroline A, Boelens Jaap Jan, Delemarre Eveline M, Drylewicz Julia, Verhoeven-Duif Nanda, van Hasselt Peter M, Nierkens Stefan 24 Aug 2021, In: Blood Advances. 5 , p. 3092-3101 10 p.

Early and Long-Term Effects of Dupilumab Treatment on Circulating T-Cell Functions in Patients with Moderate-to-Severe Atopic Dermatitis

Bakker D S, van der Wal M M, Heeb L E M, Giovannone B, Asamoah M, Delemarre E M, Drylewicz J, Nierkens S, Boyman O, de Bruin-Weller M S, Thijs J L, Wijk F van 18 Feb 2021, In: Journal of Investigative Dermatology. 141 , p. 1943-1953.e13

Cell-density independent increased lymphocyte production and loss rates post-autologous HSCT

Baliu Piqué Mariona, van Hoeven Vera, Drylewicz Julia, van der Wagen Lotte E, Janssen Anke, Otto Sigrid A, van Zelm Menno C, de Boer Rob J, Kuball Jürgen Jhe, Borghans Jose Am, Tesselaar Kiki 4 Feb 2021, In: eLife. 10 22 p.

Unraveling heterogeneity in pediatric atopic dermatitis:identification of serum biomarker based patient clusters

Bakker Daphne S, Graaf Marlies de, Nierkens Stefan, Delemarre Eveline M, Knol Edward, van Wijk Femke, de Bruin-Weller Marjolein S, Drylewicz Julia, Thijs Judith L 2021, In: The Journal of Allergy and Clinical Immunology. 149 , p. 125-134 10 p.

EASI p-EASI: Predicting disease severity in atopic dermatitis patients treated with dupilumab using a combination of serum biomarkers

Bakker Daphne S, Ariens Lieneke F M, Giovannone Barbara, Hijnen DirkJan, Delemarre Eveline M, Knol Edward, Nierkens Stefan, de Bruin-Weller Marjolein S, Thijs Judith L, Drylewicz Julia Dec 2020, In: Allergy. 75 , p. 3287-3289 3 p.

Broad proteomic screen reveals shared serum proteomic signature in patients with psoriatic arthritis and psoriasis without arthritis

Leijten Emmerik, Tao Weiyang, Pouw Juliette, van Kempen Tessa, Olde Nordkamp Michel, Balak Deepak, Tekstra J, Muñoz-Elías Ernesto, DePrimo Samuel, Drylewicz Julia, Pandit Aridaman, Boes Marianne, Radstake Timothy 13 Aug 2020, In: Rheumatology (Oxford, England). 60 , p. 751–761 11 p.

All research output

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