dr. F. (Alicia) Boxel

dr. F. (Alicia) Boxel

Assistant Professor
dr. F. (Alicia) Boxel
  • Cardiovasculaire Epi Team 7B
  • Onderzoek Precision medicine



Alicia is currently working as assistant professor in cardiovascular epidemiology, associated with the BigData@Heart consortium of the Innovative Medicines Initiative. Main fields of interest: heart failure, electronic health records, real-world data, phenotyping, causal inference and personalised medicine.

In 2016 Alicia Uijl started her PhD project on Opportunities and Challenges of Real-world Data in Heart Failure at the Julius Center for Primary Care and Health Sciences, University Medical Center Utrecht. She was under supervision of prof. dr. F.W. Asselbergs, prof. dr. A.W. Hoes, dr. S. Koudstaal and dr. I. Vaartjes.

She spent a research period abroad from September 2016 – September 2017, where she worked at the Institute for Health Informatics at University College London with CALIBER and CPRD data, United Kingdom, under supervision of dr. R.H.H. Groenwold and prof. Spiros Denaxas.

She spent a second research period abroad, at Karolinska Institutet, Sweden, where she worked from September 2018 – June 2019. Here she studied the Swedish Heart Failure registry, working together with dr. Gianluigi Savarese and prof. dr. Lars Lund. During her PhD trajectory she obtained a second Master's degree, the online post-graduate Master’s degree in Clinical Epidemiology, in 2019. In June 2020 she succesfully defended her PhD.

Research Output (20)

Methodological issues in meta-analyses of real-world clinical data to infer causality

Uijl Alicia, Lund Lars H, Asselbergs Folkert W, Savarese Gianluigi 15 Dec 2021, In: International Journal of Cardiology. 345 , p. 107-108 2 p.

Empagliflozin in Heart Failure With Predicted Preserved Versus Reduced Ejection Fraction:Data From the EMPA-REG OUTCOME Trial

Savarese Gianluigi, Uijl Alicia, Lund Lars H, Anker Stefan D, Asselbergs Folkert, Fitchett David, Inzucchi Silvio E, Koudstaal Stefan, Ofstad Anne Pernille, Schrage Benedikt, Vedin Ola, Wanner Christoph, Zannad Faiez, Zwiener Isabella, Butler Javed Aug 2021, In: Journal of Cardiac Failure. 27 , p. 888-895 8 p.

Internal-external cross-validation helped to evaluate the generalizability of prediction models in large clustered datasets

Takada Toshihiko, Nijman Steven, Denaxas Spiros, Snell Kym I E, Uijl Alicia, Nguyen Tri-Long, Asselbergs Folkert W, Debray Thomas P A 6 Apr 2021, In: Journal of Clinical Epidemiology. 137 , p. 83-91 9 p.

Temporal trends in heart failure medication prescription in a population-based cohort study

Uijl Alicia, Vaartjes Ilonca, Denaxas S, Hemingway Harry, Shah Anoop, Cleland J, Grobbee Diederick, Hoes Arno, Asselbergs Folkert W, Koudstaal Stefan 2 Mar 2021, In: BMJ Open. 11 , p. 1-9

Clinical profile and contemporary management of patients with heart failure with preserved ejection fraction:results from the CHECK-HF registry

Uijl A, Veenis J F, Brunner-La Rocca H P, van Empel V, Linssen G C M, Asselbergs F W, van der Lee C, Eurlings L W M, Kragten H, Al-Windy N Y Y, van der Spank A, Koudstaal S, Brugts J J, Hoes A W 13 Jan 2021, In: Netherlands Heart Journal. 29 , p. 370-376 7 p.

Identification of Distinct Phenotypic Clusters in Heart Failure with Preserved Ejection Fraction

Uijl Alicia, Savarese Gianluigi, Vaartjes Ilonca, Dahlström Ulf, Brugts Jasper J, Linssen Gerard Cm, van Empel Vanessa, Rocca Hans-Peter Brunner-La, Asselbergs Folkert W, Lund Lars H, Hoes Arno W, Koudstaal Stefan 2021, In: European Journal of Heart Failure. 23 , p. 973-982 10 p.

A registry-based algorithm to predict ejection fraction in patients with heart failure

Uijl Alicia, Lund Lars H, Vaartjes Ilonca, Brugts Jasper J, Linssen Gerard C, Asselbergs Folkert W, Hoes Arno W, Dahlström Ulf, Koudstaal Stefan, Savarese Gianluigi 17 Jun 2020, In: ESC heart failure. 7 , p. 2388-2397 10 p.

Antithrombotic Therapy and Major Adverse Limb Events in Patients With Chronic Lower Extremity Arterial Disease:systematic review and meta-analysis from the European Society of Cardiology Working Group on Cardiovascular Pharmacotherapy in Collaboration with the European Society of Cardiology Working Group on Aorta and Peripheral Vascular Diseases

Savarese Gianluigi, Reiner Martin F, Uijl Alicia, D Amario Domenico, Agewall Stefan, Atar Dan, Baumgartner Iris, Borghi Claudio, De Carlo Marco, Drexel Heinz, Kaski Juan Carlos, Kjeldsen Keld P, Kucher Nils, Lund Lars H, Niessner Alexander, Semb Anne Grete, Schmidt Thomas A, Sulzgruber Patrick, Tamargo Juan, Vitale Cristiana, Wassmann Sven, Aboyans Victor, Lewis Basil S 1 Apr 2020, In: European heart journal - Cardiovascular pharmacotherapy. 6 , p. 86-93 8 p.

Early recurrences of atrial tachyarrhythmias post pulmonary vein isolation

von Olshausen Gesa, Uijl Alicia, Jensen-Urstad Mats, Schwieler Jonas, Drca Nikola, Bastani Hamid, Tapanainen Jari, Saluveer Ott, Bourke Tara, Kennebäck Göran, Insulander Per, Deisenhofer Isabel, Braunschweig Frieder 26 Jan 2020, In: Journal of Cardiovascular Electrophysiology. 31 , p. 674-681 8 p.

All research output

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