M.N. (Linda) Bosma MBA

M.N. (Linda) Bosma MBA

PHD Candidate - Medical
M.N. (Linda) Bosma MBA
  • Department of General Practice



Linda Joosten studied medicine at Utrecht University and obtained her medical degree in 2016.
She started her PhD programme at the Julius Center of the UMC Utrecht in January 2017. The focus of her research is to evaluate whether the impact of a strategy aimed at switching INR-guided vitamin K antagonist management to a NOAC-based treatment strategy (non-vitamin K antagonist oral anticoagulants) is superior in terms of the occurrence of major or clinically relevant non-major bleeding complications in frail elderly patients with atrial fibrillation (FRAIL-AF study). This multicenter pragmatic randomized controlled clinical trial is supervised by dr. Geert-Jan Geersing, dr. Frans Rutten and prof. dr. Arno Hoes. 
Linda Joosten will combine her PhD programme with the Postgraduate Master of Epidemiology at Utrecht University and the General Practice Vocational Training Programme in Utrecht.

Research Output (7)

Sex- and age specific association of new-onset atrial fibrillation with in-hospital mortality in hospitalised COVID-19 patients

Offerhaus Joost A, Joosten Linda P T, van Smeden Maarten, Linschoten Marijke, Bleijendaal Hidde, Tieleman Robert, Wilde Arthur A M, Rutten Frans H, Geersing Geert-Jan, Ann Remme Carol, 4 Feb 2022, In: IJC Heart and Vasculature. 39 , p. 1-9

Safety of switching from vitamin K antagonist to non-vitamin K antagonist oral anticoagulant in frail elderly with atrial fibrillation:rationale and design of the FRAIL-AF randomised controlled trial

Joosten Linda P T, van Doorn Sander, Hoes Arno W, Nierman Melchior C, Wiersma Nynke M, Koek Huiberdina L, Hemels Martin E W, Huisman Menno V, Roes Kit C, van den Bor Rutger M, Buding Wim F, Rutten Frans H, Geersing Geert-Jan 29 Dec 2019, In: BMJ Open. 9

Ontwikkelingen in prevalentie van atriumfibrilleren en antitrombotica voorschriften

Joosten Linda, van Eerde E.J.B., Rutten Frans H, Geersing Geert Jan 6 Dec 2019, p. 123 136 p.

Antistolling bij patiënten met atriumfibrilleren

Trinks-Roerdink Emmy, Joosten Linda Sep 2019, In: Huisarts en Wetenschap. 62 , p. 64-64 1 p.

Stroke Rate Variation and Anticoagulation Benefit in Atrial Fibrillation

Joosten Linda P.T., Van Doorn Sander, Rutten Frans H., Geersing Geert Jan 4 Jun 2019, In: Annals of Internal Medicine. 170 , p. 816-817 2 p.

Welke DoAC bij patiënten met atriumfibrilleren?

Joosten Linda, Geersing Geert Jan 1 Jan 2018, In: Nederlands Tijdschrift voor Geneeskunde. 162

Het FRAIL-AF onderzoek: Optimale anticoagulantia bij kwetsbare ouderen

Joosten Linda, Wiersma Nynke 2018, In: Tijdschrift voor trombose en antistolling. 46 , p. 23-23 1 p.

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