ir. drs. W.X. (Kathelijn) Bastiaan

ir. drs. W.X. (Kathelijn) Bastiaan

Associate Professor - medical
ir. drs. W.X. (Kathelijn) Bastiaan
  • Hematology/Van Creveldclinic

Research Programs



Kathelijn Fischer has been working at the University Medical Center Utrecht, both as a Paediatric Haematologist and a Clinical Epidemiologist.

Dr Fischer finished her medical training in 1988 is a registered paediatrician since 1994. Dr Fischer specialized in paediatric haematology and oncology in Utrecht, the Netherlands. Subsequently, she performed PhD research in haemophilia while training as a clinical epidemiologist. She published her thesis on ‘Treatment strategies in severe haemophilia: in search for the optimal treatment’ in 2001.

Dr Fischer supervises four PhD students and served as co-promotor for seven other PhD students in the field of haematology, neurology and gynaecology.

Dr Fischer is principal investigator in several international studies on long-term results of haemophilia treatment, and is the epidemiologist for the European Haemophilia Safety Surveillance Study (EUHASS-member of the steering committee) as well as for the European PedNet registry.

The specific areas of expertise and interest of dr Fischer include the epidemiology of haemophilia (including use of registries), prophylactic treatment, and outcome assessment in haemophilia care.

Side Activities

  • Membership of international working groups: International Prophylaxis Study Group (IPSG), European Association for Haemophilia and Allied Disorders (EAHAD; former EC member), she is a former co-chair of the FVIII/IX SSC subcommittee of the ISTH and participated in the group that drafted the Principles of Haemophilia Care.
  • Member of the National Haemophilia Registry Committee of the Dutch Haemophilia Treaters Board (NVHB)
  • Membership professional organisations: NVK (Dutch Paediatric Society,- section benign haematology), ISTH (International Society for Thrombosis and Haemostasis), WFH (World Federation for Haemophilia)
  • Section editor for Thrombosis and Haemostasis journal, member of the editorial board for Haemophilia journal

Fellowship and Awards

Bayer Haemophilia Special Project Award (2005)

Research Output (310)

Predicting Individual Changes in Terminal Half-Life After Switching to Extended Half-Life Concentrates in Patients With Severe Hemophilia

Versloot Olav, Iserman Emma, Chelle Pierre, Germini Federico, Edginton Andrea N, Schutgens Roger E G, Iorio Alfonso, Fischer Kathelijn Apr 2022, In: HemaSphere. 6

Modeling Benefits, Costs, and Affordability of a Novel Gene Therapy in Hemophilia A

Ten Ham Renske M T, Walker Sikon M, Soares Marta O, Frederix Geert W J, Leebeek Frank W G, Fischer Kathelijn, Coppens Michiel, Palmer Stephen J 28 Feb 2022, In: HemaSphere. 6 , p. 1-11

Is pharmacokinetic-guided dosing of desmopressin and von Willebrand factor-containing concentrates in individuals with von Willebrand disease or low von Willebrand factor reliable and feasible? A protocol for a multicentre, non-randomised, open label cohort trial, the OPTI-CLOT:To WiN study

Heijdra Jessica M., Al Arashi Wala, De Jager Nico C.B., Cloesmeijer Michael E., Bukkems Laura H., Zwaan Christian M., Leebeek Frank W.G., Mathôt Ron A.A., Cnossen Marjon H., Cnossen M. H., Leebeek F. W.G., Zwaan Christian M., Van Vliet I., Fijnvandraat K., Mathot R. A.A., Meijer K., Kruip M. J.H.A., S Polinder Polinder, Coppens M., Tamminga R. Y.J., Meijer K., Laros-Van B. A.P., Brons P., Schols S. E.M., Van Der Meer F. J.M., Eikenboom H. C.J., Schutgens R. E.G., Fischer K., Heubel-Moenen F., Nieuwenhuizen L., Ypma P., Driessens M. H.E., Pw Collins Collins, Liesner R., Chowdary P., Keeling D. 15 Feb 2022, In: BMJ Open. 12 , p. 1-6

Bone mineral density in haemophilia - a multicentre study evaluating the impact of different replacement regimens

Klintman Jenny, Akesson Kristina E, Holme Pål André, Fischer Kathelijn 7 Jan 2022, In: Haemophilia. 28 , p. 239-246 8 p.

Reduced cardiovascular morbidity in patients with hemophilia:results of a 5-year multinational prospective study

Van Der Valk Paul, Makris Michael, Fischer Kathelijn, Tait Robert C, Chowdary Pratima, Collins Peter W, Meijer Karina, van Vulpen Lize F D, Mauser-Bunschoten Eveline, Schutgens Roger E G 8 Dec 2021, In: Blood Advances. 6 , p. 902-908 7 p.

Detecting low blood concentrations in joints using T1 and T2 mapping at 1.5, 3, and 7 T:an in vitro study

van Leeuwen Flora H P, Lena Beatrice, Zwanenburg Jaco J M, van Vulpen Lize F D, Bartels Lambertus W, Fischer Kathelijn, Nap Frank J, de Jong Pim A, Bos Clemens, Foppen Wouter 2 Dec 2021, In: European radiology experimental. 5

Generic PROMIS item banks in adults with hemophilia for patient-reported outcome assessment:Feasibility, measurement properties, and relevance

Kuijlaars Isolde A R, Teela Lorynn, van Vulpen Lize F D, Timmer Merel A, Coppens Michiel, Gouw Samantha C, Peters Marjolein, Kruip Marieke J H A, Cnossen Marjon H, Muis Jelmer J, van Hoorn Evelien S, Haverman Lotte, Fischer Kathelijn Dec 2021, In: Research and practice in thrombosis and haemostasis. 5 , p. 1-14

Hepatitis C virus in hemophilia:Health-related quality of life after successful treatment in the sixth Hemophilia in the Netherlands study

Isfordink Cas J, Gouw Samantha C, van Balen Erna C, Hassan Shermarke, Beckers Erik A M, van der Bom Johanna G, Coppens Michiel, Eikenboom Jeroen, Fischer Kathelijn, Hooimeijer Louise, Leebeek Frank W G, Rosendaal Frits R, Schols Saskia E M, Smit Cees, van Vulpen Lize F D, Mauser-Bunschoten Eveline P Dec 2021, In: Research and practice in thrombosis and haemostasis. 5 , p. 1-11


Berntorp Erik, Fischer Kathelijn, Hart Daniel P., Mancuso Maria Elisa, Stephensen David, Shapiro Amy D., Blanchette Victor Dec 2021, In: Nature Reviews Disease Primers. 7

A qualitative study on the experiences of haemophilia carriers before, during and after pregnancy

Punt Marieke C., Teela Lorynn, Fischer Kathelijn, Bloemenkamp Kitty W.M., Lely A. Titia, Driessens Mariette H.E., Pekel Lynnda, Haverman Lotte, van Galen Karin P.M. Nov 2021, In: Haemophilia. 27 , p. e675-e682

All research output

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