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Extracellular Vesicles in Atherosclerosis

Extracellular Vesicles in Atherosclerosis

Research Topics uitklapper, klik om te openen

For further reading, see here.

Key Publications uitklapper, klik om te openen

1: Dekker M, Waissi F, van Bennekom J, Silvis MJM, Timmerman N, Bank IEM, Walter JE, Mueller C, Schoneveld AH, Schiffelers RM, Pasterkamp G, Grobbee DE, de Winter RJ, Mosterd A, de Kleijn DPV, Timmers L. Plasma extracellular vesicle proteins are associated with stress-induced myocardial ischemia in women presenting with chest pain. Sci Rep. 2020 Jul 23;10(1):12257. doi:10.1038/s41598-020-69297-0. PMID: 32704130; PMCID: PMC7378184.

2: Silvis MJM, van Hout GPJ, Fiolet ATL, Dekker M, Bosch L, van Nieuwburg MMJ, Visser J, Jansen MS, Timmers L, de Kleijn DPV. Experimental parameters and infarct size in closed chest pig LAD ischemia reperfusion models; lessons learned. BMC Cardiovasc Disord. 2021 Apr 12;21(1):171. doi:10.1186/s12872-021-01995-7. PMID: 33845779; PMCID: PMC8042863.

3: Silvis MJM, Fiolet ATL, Opstal TSJ, Dekker M, Suquilanda D, Zivkovic M,Duyvendak M, The SHK, Timmers L, Bax WA, Mosterd A, Cornel JH, de Kleijn DPV. Colchicine reduces extracellular vesicle NLRP3 inflammasome protein levels in chronic coronary disease: A LoDoCo2 biomarker substudy. Atherosclerosis. 2021 Aug 11;334:93-100. doi: 10.1016/j.atherosclerosis.2021.08.005. Epub ahead of print. PMID: 34492522.

4: Timmerman N, Waissi F, Dekker M, van de Pol QY, van Bennekom J, Schoneveld A, klein Avink MJM, de Winter RJ, Pasterkamp G, de Borst GJ de Kleijn DPV. Pre-Operative Plasma Extracellular Vesicle Proteins are Associated with a High Risk of Long Term Secondary Major Cardiovascular Events in Patients Undergoing Carotid Endarterectomy. Eur. J. Vasc & Endovasc. Surg. 2021 available on line https://doi.org/10.1016/j.ejvs.2021.06.039

5: Schnitzler JG, Hoogeveen RM, Ali L, Prange KHM, Waissi F, van Weeghel M, Bachmann JC, Versloot M, Borrelli MJ, Yeang C, De Kleijn DPV, Houtkooper RH, Koschinsky ML, de Winther MPJ, Groen AK, Witztum JL, Tsimikas S, Stroes ESG, Kroon J. Atherogenic Lipoprotein(a) Increases Vascular Glycolysis, Thereby Facilitating Inflammation and Leukocyte Extravasation. Circ Res. 2020 May 8;126(10):1346-1359. doi: 10.1161/CIRCRESAHA.119.316206. Epub 2020 Mar 12. PMID:32160811; PMCID: PMC7208285.

Facilities Involved uitklapper, klik om te openen

Athero-Express

Myomarker

Minerva

Lodoco2

OLINK platform

People Involved uitklapper, klik om te openen

Contact uitklapper, klik om te openen

Dominique de Kleijn

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