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ir. drs. W.X. (Jacco) van Oostvogels

ir. drs. W.X. (Jacco) van Oostvogels

Full Professor

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Research Output (53)

Probing the Tumor Suppressor Function of BAP1 in CRISPR-Engineered Human Liver Organoids

Artegiani Benedetta, van Voorthuijsen Lisa, Lindeboom Rik G.H., Seinstra Daniëlle, Heo Inha, Tapia Pablo, López-Iglesias Carmen, Postrach Daniel, Dayton Talya, Oka Rurika, Hu Huili, van Boxtel Ruben, van Es Johan H., Offerhaus Johan, Peters Peter J., van Rheenen Jacco, Vermeulen Michiel, Clevers Hans 6 Jun 2019, In: Cell Stem Cell. 24 , p. 927-943.e6

Intravital imaging of glioma border morphology reveals distinctive cellular dynamics and contribution to tumor cell invasion

Alieva Maria, Leidgens Verena, Riemenschneider Markus J., Klein Christoph A., Hau Peter, van Rheenen Jacco 14 Feb 2019, In: Scientific Reports. 9

Wnt ligands influence tumour initiation by controlling the number of intestinal stem cells

Huels D. J., Bruens L., Hodder M. C., Cammareri P., Campbell A. D., Ridgway R. A., Gay D. M., Solar-Abboud M., Faller W. J., Nixon C., Zeiger L. B., McLaughlin M. E., Morrissey E., Winton D. J., Snippert H. J., Van Rheenen J., Sansom O. J. 1 Dec 2018, In: Nature Communications. 9

Cancer cells copy migratory behavior and exchange signaling networks via extracellular vesicles

Steenbeek Sander C., Pham Thang V., de Ligt Joep, Zomer Anoek, Knol Jaco C., Piersma Sander R., Schelfhorst Tim, Huisjes Rick, Schiffelers Raymond M., Cuppen Edwin, Jimenez Connie R., van Rheenen Jacco 1 Aug 2018, In: EMBO Journal. 37

Inflammation-sensitive myosin-x functionally supports leukocyte extravasation by Cdc42-mediated ICAM-1-rich endothelial filopodia formation

Kroon Jeffrey, Schaefer Antje, Van Rijssel Jos, Hoogenboezem Mark, Van Alphen Floris, Hordijk Peter, Stroes Erik S.G., Strömblad Staffan, Van Rheenen Jacco, Van Buul Jaap D. 1 Mar 2018, In: Journal of Immunology. 200 , p. 1790-1801 12 p.

Quantifying exosome secretion from single cells reveals a modulatory role for GPCR signaling

Verweij Frederik Johannes, Bebelman Maarten P., Jimenez Connie R., Garcia-Vallejo Juan J., Janssen Hans, Neefjes Jacques, Knol Jaco C., de Goeij-de Haas Richard, Piersma Sander R., Baglio S. Rubina, Verhage Matthijs, Middeldorp Jaap M., Zomer Anoek, van Rheenen Jacco, Coppolino Marc G., Hurbain Ilse, Raposo Graça, Smit Martine J., Toonen Ruud F.G., van Niel Guillaume, Pegtel D. Michiel 1 Mar 2018, In: Journal of Cell Biology. 217 , p. 1129-1142 14 p.

Specific Labeling of Stem Cell Activity in Human Colorectal Organoids Using an ASCL2-Responsive Minigene

Oost Koen C., van Voorthuijsen Lisa, Fumagalli Arianna, Lindeboom Rik G.H., Sprangers Joep, Omerzu Manja, Rodriguez-Colman Maria J., Heinz Maria C., Verlaan-Klink Ingrid, Maurice Madelon M., Burgering Boudewijn M.T., van Rheenen Jacco, Vermeulen Michiel, Snippert Hugo J.G. 6 Feb 2018, In: Cell Reports [E]. 22 , p. 1600-1614 15 p.

A surgical orthotopic organoid transplantation approach in mice to visualize and study colorectal cancer progression

Fumagalli Arianna, Suijkerbuijk Saskia J.E., Begthel Harry, Beerling Evelyne, Oost Koen C., Snippert Hugo J., Van Rheenen Jacco, Drost Jarno 1 Feb 2018, In: Nature Protocols. 13 , p. 235-247 13 p.

Glycosylated extracellular vesicles released by glioblastoma cells are decorated by CCL18 allowing for cellular uptake via chemokine receptor CCR8

Berenguer Jordi, Lagerweij Tonny, Zhao Xi Wen, Dusoswa Sophie, van der Stoop Petra, Westerman Bart, Gooijer Mark C.de, Zoetemelk Marloes, Zomer Anoek, Crommentuijn Matheus H.W., Wedekind Laurine E., López-López Àlan, Giovanazzi Alberta, Bruch-Oms Marina, Meulen-Muileman Ida H.van der, Reijmers Rogier M., van Kuppevelt Toin H., García-Vallejo Juan Jesús, van Kooyk Yvette, Tannous Bakhos A., Wesseling Pieter, Koppers-Lalic Danijela, Vandertop W. Peter, Noske David P., van Beusechem Victor W., van Rheenen Jacco, Pegtel D. Michiel, Tellingen Olaf van, Wurdinger Thomas 1 Jan 2018, In: Journal of Extracellular Vesicles. 7

Preventing inflammation inhibits biopsy-mediated changes in tumor cell behavior

Alieva Maria, Margarido Andreia S., Wieles Tamara, Abels Erik R., Colak Burcin, Boquetale Carla, Jan Noordmans Herke, Snijders Tom J., Broekman Marike L., Van Rheenen Jacco 1 Dec 2017, In: Scientific Reports. 7

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