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ir. T. Straaten

ir. T. Straaten

Assistant Professor - medical
ir. T. Straaten
  • Onderzoek

Fellowship and Awards

Honours:

Senior Scottish Clinical Fellowship award (NRS) (2016)

Innovational Research Incentives Scheme: Vidi laureate (NWO) (2015)

Innovational Research Incentives Scheme: Veni laureate (NWO) (2009)

Ter Meulen Fund Stipends, KNAW (2006/2007)

Prof. Dr. Burema award for most relevant publication in the field of infectious diseases 2004/2005, The Municipal Health Service Rotterdam and Environs (GGD), The Netherlands

Investigator award 2004/2005, Erasmus MC-Sophia Children’s award, Rotterdam, The Netherlands

Young investigator award 2004, Pediatric Association of The Netherlands (NVK), The Netherlands

Prof. Dr. J.C. Birkenhäger award 2003 for excellence in research and presentation, Erasmus MC, Rotterdam, The Netherlands

Grants:

2017. Spain. Ramon Areces Foundation: Personal grant of postdoctoral fellow Dr. Alicia Ruiz for a 2-year postdoc in my group to study mycobiome-microbiome interaction. Stipend

2017. NIHR.Global health research unit: Collaborator of NIHR RESPIRE Unit, University of Edinburgh. £6.000.000

2017. NIHR. Global health research unit. Collaborator and Steering Committee member of NIHR MPRU Unit, University College London. £6.000.000

2016-2012. NRS. SSCF. Hhost-microbiome interactions: identification of ecological drivers that are key to respiratory problems in pre-term born children (Scottish Senior Clinical Fellowship). £800.000

2015-2019 ZonMW. Vidi grant. Host-microbiome interactions: the key to respiratory health? (Personal career grant) €800.000

2014-2017. ZonMW. Priority Medicines. Consequences of early-life antibiotic exposure on AMR gene selection: what regimen causes least harm? (PI) €400.000

2014-2016. Gates Foundation. Effect of live attenuated Influenza vaccines on experimental human pneumococcal carriage.€250.000

2012-2014. Ministry of economic affaires. TKI grant.“Food for life solutions” (co-applicant). €130.000 (of 1.0 million)

2011-2014 TI Pharma. Collaboratiive grant. Therapeutic effect of an extensively hydrolyzed infant formula on atopic dermatitis” (participant) €100.000 (of 1.5 million)

2009-2014. NWO/ZonMW. Top grant. “Dynamics of nasopharyngeal colonization of microflora; the key to respiratory disease?” (PI). €625.000

2009-2012. NWO. Veni grant.“Nasopharyngeal microbial communities and the effects of vaccination” (Personal career grant). €250.000

2006-2008. KNAW. Ter Meulen Fund. “Interaction between Streptococcus pneumoniae and the maturing host immune system” (personal career grant). €100.000

2009-2013. Local hospital fund (based on private donations). Friends of WKZ. Respiratory microbiome development in healthy children in relation to delivery mode €150.000/ Respiratory microbiome development in infants with cystic fibrosis and controls. €240.000

2012. Local. WKZ. “Leading ladies in science” unrestricted grant. €100.000

Research Output (132)

Effects of early-life antibiotics on the developing infant gut microbiome and resistome:a randomized trial

Reyman Marta, van Houten Marlies A., Watson Rebecca L., Chu Mei Ling J.N., Arp Kayleigh, de Waal Wouter J., Schiering Irene, Plötz Frans B., Willems Rob J.L., van Schaik Willem, Sanders Elisabeth A.M., Bogaert Debby 16 Feb 2022, In: Nature Communications. 13

Salivary antibody responses to ten-valent pneumococcal conjugate vaccination following two different immunization schedules in a healthy birth cohort

de Koff Emma M., van Houten Marlies A., de Heij Femke, Berbers Guy A.M., Bogaert Debby, Sanders Elisabeth A.M. 24 Jan 2022, In: Vaccine. 40 , p. 408-413 6 p.

Topical or oral antibiotics for children with acute otitis media presenting with ear discharge:study protocol of a randomised controlled non-inferiority trial

Hullegie Saskia, Venekamp Roderick P, van Dongen Thijs M A, Mulder Sanne, van Schaik Willem, de Wit G Ardine, Hay Alastair D, Little Paul, Moore Michael V, Sanders Elisabeth A M, Bonten Marc J M, Bogaert Debby, Schilder Anne Gm, Damoiseaux Roger A M J 16 Dec 2021, In: BMJ Open. 11

Distinct patterns of within-host virus populations between two subgroups of human respiratory syncytial virus

Lin Gu Lung, Drysdale Simon B., Snape Matthew D., O’Connor Daniel, Brown Anthony, MacIntyre-Cockett George, Mellado-Gomez Esther, de Cesare Mariateresa, Bonsall David, Ansari M. Azim, Öner Deniz, Aerssens Jeroen, Butler Christopher, Bont Louis, Openshaw Peter, Martinón-Torres Federico, Nair Harish, Bowden Rory, Campbell Harry, Cunningham Steve, Bogaert Debby, Beutels Philippe, Wildenbeest Joanne, Clutterbuck Elizabeth, McGinley Joseph, Thwaites Ryan, Wiseman Dexter, Gómez-Carballa Alberto, Rodriguez-Tenreiro Carmen, Rivero-Calle Irene, Dacosta-Urbieta Ana, Heikkinen Terho, Meijer Adam, Fischer Thea Kølsen, van den Berge Maarten, Giaquinto Carlo, Abram Michael, Dormitzer Philip, Stoszek Sonia, Gallichan Scott, Rosen Brian, Molero Eva, Machin Nuria, Spadetto Martina, Golubchik Tanya, Pollard Andrew J., Dec 2021, In: Nature Communications. 12 , p. 1-11 11 p.

The effect of live attenuated influenza vaccine on pneumococcal colonisation densities among children aged 24–59 months in The Gambia:a phase 4, open label, randomised, controlled trial

Peno Chikondi, Armitage Edwin P., Clerc Melanie, Balcazar Lopez Carlos, Jagne Ya Jankey, Drammeh Sainabou, Jarju Sheikh, Sallah Hadijatou, Senghore Elina, Lindsey Benjamin B., Camara Janko, Bah Sulayman, Mohammed Nuredin I., Dockrell David H., Kampmann Beate, Clarke Ed, Bogaert Debby, de Silva Thushan I. Dec 2021, In: The Lancet Microbe. 2 , p. e656-e665

Decreased production of epithelial-derived antimicrobial molecules at mucosal barriers during early life

Lokken-Toyli Kristen L., de Steenhuijsen Piters Wouter A.A., Zangari Tonia, Martel Rachel, Kuipers Kirsten, Shopsin Bo, Loomis Cynthia, Bogaert Debby, Weiser Jeffrey N. Nov 2021, In: Mucosal immunology. 14 , p. 1358-1368 11 p.

A novel method to standardise serum IgA measurements shows an increased prevalence of IgA deficiency in young children with recurrent respiratory tract infections

Koenen Mischa, Bosma Marleen, Roorda Udo, Wopereis Fabienne, Roos Anja, van der Vries Erhard, Bogaert D, Sanders Elisabeth , Boes Marianne, Heidema Jojanneke, van Montfrans JM, Balemans Walter A F, van Holten Thijs C, Verhagen Lilly 29 Oct 2021, In: Clinical and Translational Immunology. 10 10 p.

Microbial community networks across body sites are associated with susceptibility to respiratory infections in infants

Reyman Marta, Clerc Melanie, van Houten Marlies A., Arp Kayleigh, Chu Mei Ling J.N., Hasrat Raiza, Sanders Elisabeth A.M., Bogaert Debby 28 Oct 2021, In: Communications biology. 4

Publisher Correction::Distinct patterns of within-host virus populations between two subgroups of human respiratory syncytial virus

Lin Gu Lung, Drysdale Simon B., Snape Matthew D., O’Connor Daniel, Brown Anthony, MacIntyre-Cockett George, Mellado-Gomez Esther, de Cesare Mariateresa, Bonsall David, Ansari M. Azim, Öner Deniz, Aerssens Jeroen, Butler Christopher, Bont Louis, Openshaw Peter, Martinón-Torres Federico, Nair Harish, Bowden Rory, Campbell Harry, Cunningham Steve, Bogaert Debby, Beutels Philippe, Wildenbeest Joanne, Clutterbuck Elizabeth, McGinley Joseph, Thwaites Ryan, Wiseman Dexter, Gómez-Carballa Alberto, Rodriguez-Tenreiro Carmen, Rivero-Calle Irene, Dacosta-Urbieta Ana, Heikkinen Terho, Meijer Adam, Fischer Thea Kølsen, van den Berge Maarten, Giaquinto Carlo, Abram Michael, Dormitzer Philip, Stoszek Sonia, Gallichan Scott, Rosen Brian, Molero Eva, Machin Nuria, Spadetto Martina, Golubchik Tanya, Pollard Andrew J., 7 Oct 2021, In: Nature Communications. 12 , p. 1

Benchmarking laboratory processes to characterise low-biomass respiratory microbiota

Hasrat Raiza, Kool Jolanda, de Steenhuijsen Piters Wouter A.A., Chu Mei Ling J.N., Kuiling Sjoerd, Groot James A., van Logchem Elske M., Fuentes Susana, Franz Eelco, Bogaert Debby, Bosch Thijs 25 Aug 2021, In: Scientific Reports. 11 13 p.

All research output

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