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dr. A.J. (Alex) Poot

dr. A.J. (Alex) Poot

Associate Professor
dr. A.J. (Alex) Poot
  • 7T Group

Research Programs

Strategic Program Cancer

Biography

Biography

Associate Professor, Head of Radionuclide Pharmacy

Research interests:

- Development of theranostics for (pediatric) cancer

- Radiochemistry

- Clinical translation and implementation

- GMP

Department:

Nucleaire Geneeskunde, Radionucliden Apotheek

Radionuclide pharmacy (text in Dutch):

De radionuclide apotheek richt zich op de ontwikkeling en klinische translatie van radioactief gelabelde moleculen voor diagnostiek en therapie, ook wel theranostics genoemd. De ontwikkeling van theranostics gaan in hoog tempo. Ondanks de grote potentie die theranostics hebben is hier voor kinderkanker nauwelijks nog aandacht voor. In een samenwerking tussen het UMC Utrecht en het Prinses Maxima Centrum richt het theranostics programma zich op deze klinische behoefte voor betere nucleaire diagnostiek en de ontwikkeling van innovatieve nucleaire behandelmogelijkheden voor kinderkanker.

Publications

- See PubMed >

- See Web of science >

Associate Professor lecture (2021) >

Research Output (8)

Biologicals as theranostic vehicles in paediatric oncology

Niessen Veerle J A, Wenker Sylvia T M, Lam Marnix G E H, van Noesel Max M, Poot Alex J 14 Sep 2022, In: Nuclear medicine and biology. 114-115 , p. 58-64 7 p.

[F-18]metafluorobenzylguanidine (MFBG) PET-CT vs. [I-123]metaiodobenzylguanidine (MIBG) imaging in neuroblastoma patients

Samim A., Tytgat G. A., Blom T., Poot A. J., Tolboom N., Braat A. J., van Noesel M. M., Lam M. G., de Keizer B. Sep 2021, In: European Journal of Nuclear Medicine and Molecular Imaging. 48 , p. S320-S320

Performance of nanoScan PET/CT and PET/MR for quantitative imaging of F-18 and Zr-89 as compared with ex vivo biodistribution in tumor-bearing mice

Chomet Marion, Schreurs Maxime, Vos Ricardo, Verlaan Mariska, Kooijman Esther J, Poot Alex J, Boellaard Ronald, Windhorst Albert D, van Dongen Guus Ams, Vugts Danielle J, Huisman Marc C, Beaino Wissam 12 Jun 2021, In: EJNMMI Research. 11 , p. 57

Identifying advanced stage NSCLC patients who benefit from afatinib therapy using 18F-afatinib PET/CT imaging

van de Stadt Eveline A, Yaqub Maqsood, Lammertsma Adriaan A, Poot Alex J, Schuit Robert C, Remmelzwaal Sharon, Schwarte Lothar A, Smit Egbert F, Hendrikse Harry, Bahce Idris May 2021, In: Lung Cancer. 155 , p. 156-162 7 p.

Nuclear Medicine Imaging in Neuroblastoma:Current Status and New Developments

Samim Atia, Tytgat Godelieve A M, Bleeker Gitta, Wenker Sylvia T M, Chatalic Kristell L S, Poot Alex J, Tolboom Nelleke, van Noesel Max M, Lam Marnix G E H, de Keizer Bart 4 Apr 2021, In: Journal of Personalized Medicine. 11 , p. 1-22

Head-to-head comparison of DFO* and DFO chelators:selection of the best candidate for clinical <sup>89</sup>Zr-immuno-PET

Chomet Marion, Schreurs Maxime, Bolijn Maria J., Verlaan Mariska, Beaino Wissam, Brown Kari, Poot Alex J., Windhorst Albert D., Gill Herman, Marik Jan, Williams Simon, Cowell Joseph, Gasser Gilles, Mindt Thomas L., van Dongen Guus A.M.S., Vugts Danielle J. Mar 2021, In: European Journal of Nuclear Medicine and Molecular Imaging. 48 , p. 694-707 14 p.

Microfluidic preparation of<sup>89</sup> zr-radiolabelled proteins by flow photochemistry

Earley Daniel F., Guillou Amaury, van der Born Dion, Poot Alex J., Holland Jason P. Feb 2021, In: Molecules. 26

The Current Status and Future Potential of Theranostics to Diagnose and Treat Childhood Cancer

Poot Alex J, Lam Marnix G E H, van Noesel Max M 19 Nov 2020, In: Frontiers in oncology. 10 , p. 1-8

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