dr. I.J.J. (René) Planting

dr. I.J.J. (René) Planting

Full Professor
dr. I.J.J. (René) Planting
  • Department of Biostatistics and Research Support
  • Julius Center Research Program Infectious Diseases
  • Julius Center Research Program Methodology



Rene Eijkemans obtained an MSc in Mathematics from Delft University of Technology.  He has been working as a researcher and statistical consultant in a wide variety of clinical settings: cardiology, cancer, gynecology, thoracic and general surgery and virology, with an emphasis on prediction models in reproductive medicine.  In total, he has (co)authored more than 80 international peer reviewed articles on predictive models, with various clinical purposes, in reproductive medicine, making him world-leading in that area.  he has gradually shifted his focus to 'omics' research and machine learning. His current research topic, ‘making prediction and classification modelling more clinically useful’, is the natural confluence of these activities in machine learning, his experience in a variety of clinical settings and his knowledge of what is required for clinical application of predictive models.

Side Activities

Chair of the Finance and Budget Committee of  the International Biometric Society (IBS) (not payed)

National representative and Member of the Representative Councel of the International Biometric Society (IBS) (not payed)

External Expert Statistical Advisory board NederlandseHartRegistratie (NHR) (expenses are payed to UMC)

Incidental statistical advice for Ferring Farmaceutical Company (payed to UMC)

Fellowship and Awards


Research Output (292)

Individual treatment effect estimation in the presence of unobserved confounding using proxies:a cohort study in stage III non-small cell lung cancer

van Amsterdam Wouter A C, Verhoeff Joost J C, Harlianto Netanja I, Bartholomeus Gijs A, Puli Aahlad Manas, de Jong Pim A, Leiner Tim, van Lindert Anne S R, Eijkemans Marinus J C, Ranganath Rajesh 7 Apr 2022, In: Scientific Reports. 12

Prediction of Real-World Long-Term Outcomes of People with CF Homozygous for the F508del Mutation Treated with CFTR Modulators

Muilwijk Danya, Bierlaagh Marlou, van Mourik Peter, Kraaijkamp Jasmijn, van der Meer Renske, van den Bor Rutger, Heijerman Harry, Eijkemans René, Beekman Jeffrey, van der Ent Kors 16 Dec 2021, In: Journal of Personalized Medicine. 11 , p. 1-12

Innovating Clinical Trials for Amyotrophic Lateral Sclerosis:Challenging the Established Order

van Eijk Ruben P A, Nikolakopoulos Stavros, Roes Kit C B, Kendall Lindsay, Han Steve S, Lavrov Arseniy, Epstein Noam, Kliest Tessa, de Jongh Adriaan D, Westeneng Henk-Jan, Al-Chalabi Ammar, Van Damme Philip, Hardiman Orla, Shaw Pamela J, McDermott Christopher J, Eijkemans Marinus J C, van den Berg Leonard H 27 Jul 2021, In: Neurology. 97 , p. 528-536 9 p.

Reply:Endometrial scratching for embryo implantation failure

van Hoogenhuijze N E, Eijkemans M J C, Broekmans F J M 20 Mar 2021, In: Human Reproduction. 36 , p. 1450-1451 2 p.

An old friend who has overstayed their welcome:the ALSFRS-R total score as primary endpoint for ALS clinical trials

van Eijk Ruben P A, de Jongh Adriaan D, Nikolakopoulos Stavros, McDermott Christopher J, Eijkemans Marinus J C, Roes Kit C B, van den Berg Leonard H 22 Jan 2021, In: Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 22 , p. 300-307 8 p.

Developing more generalizable prediction models from pooled studies and large clustered data sets

de Jong Valentijn M.T., Moons Karel G.M., Eijkemans Marinus J.C., Riley Richard D., Debray Thomas P.A. 2021, In: Statistics in Medicine. 40 , p. 3533-3559 27 p.

Developing excellence in biostatistics leadership, training and science in Africa:How the Sub-Saharan Africa Consortium for Advanced Biostatistics (SSACAB) training unites expertise to deliver excellence

Chirwa Tobias F, Matsena Zingoni Zvifadzo, Munyewende Pascalia, Manda Samuel O, Mwambi Henry, Kandala Ngianga-Bakwin, Kinyanjui Samson, Young Taryn, Musenge Eustasius, Simbeye Jupiter, Musonda Patrick, Mahande Michael Johnson, Weke Patrick, Onyango Nelson Owuor, Kazembe Lawrence, Tumwesigye Nazarius Mbona, Zuma Khangelani, Yende-Zuma Nonhlanhla, Omanyondo Ohambe Marie-Claire, Kweku Emmanuel Nakua, Maposa Innocent, Ayele Birhanu, Achia Thomas, Machekano Rhoderick, Thabane Lehana, Levin Jonathan, Eijkemans Marinus J C, Carpenter James, Chasela Charles, Klipstein-Grobusch Kerstin, Todd Jim 22 Dec 2020, In: AAS open research. 3 , p. 1-21

Endometrial scratching in women with one failed IVF/ICSI cycle-outcomes of a randomised controlled trial (SCRaTCH)

van Hoogenhuijze N E, Mol F, Laven J S E, Groenewoud E R, Traas M A F, Janssen C A H, Teklenburg G, de Bruin J P, van Oppenraaij R H F, Maas J W M, Moll E, Fleischer K, van Hooff M H A, de Koning C H, Cantineau A E P, Lambalk C B, Verberg M, van Heusden A M, Manger A P, van Rumste M M E, van der Voet L F, Pieterse Q D, Visser J, Brinkhuis E A, den Hartog J E, Glas M W, Klijn N F, van der Meer S, Bandell M L, Boxmeer J C, van Disseldorp J, Smeenk J, van Wely M, Eijkemans M J C, Torrance H L, Broekmans F J M 8 Dec 2020, In: Human Reproduction. 36 , p. 87-98 12 p.

Effect of disease related biases on the subjective assessment of social functioning in Alzheimer's disease and schizophrenia patients

Jongs Niels, Penninx Brenda, Arango Celso, Ayuso-Mateos Jose Luis, van der Wee Nic, Rossum Inge Winter-van, Saris Ilja M J, van Echteld Amber, Koops Sanne, Bilderbeck Amy C, Raslescu Andreea, Dawson Gerard R, Sommer Bernd, Marston Hugh, Vorstman Jacob A, Eijkemans Marinus Jc, Kas Martien J 9 Nov 2020, In: Journal of Psychiatric Research. 145 , p. 302-308 7 p.

Systematic review of statistical methods for safety data in malaria chemoprevention in pregnancy trials

Patson Noel, Mukaka Mavuto, Otwombe Kennedy N, Kazembe Lawrence, Mathanga Don P, Mwapasa Victor, Kabaghe Alinune N, Eijkemans Marinus J C, Laufer Miriam K, Chirwa Tobias 20 Mar 2020, In: Malaria Journal. 19 , p. 119

All research output

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