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drs. R.S.S. (Wigard) Meijering

drs. R.S.S. (Wigard) Meijering

Associate Professor

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Research Output (91)

An organoid platform for ovarian cancer captures intra- and interpatient heterogeneity

Kopper Oded, de Witte Chris J, Lõhmussaar Kadi, Valle-Inclan Jose Espejo, Hami Nizar, Kester Lennart, Balgobind Anjali Vanita, Korving Jeroen, Proost Natalie, Begthel Harry, van Wijk Lise M, Revilla Sonia Aristín, Theeuwsen Rebecca, van de Ven Marieke, van Roosmalen Markus J, Ponsioen Bas, Ho Victor W H, Neel Benjamin G, Bosse Tjalling, Gaarenstroom Katja N, Vrieling Harry, Vreeswijk Maaike P G, van Diest Paul J, Witteveen Petronella O, Jonges Trudy, Bos Johannes L, van Oudenaarden Alexander, Zweemer Ronald P, Snippert Hugo J G, Kloosterman Wigard P, Clevers Hans May 2019, In: Nature Medicine. 25 , p. 838-849 12 p.

Skewed X-inactivation is common in the general female population

Shvetsova Ekaterina, Sofronova Alina, Monajemi Ramin, Gagalova Kristina, Draisma Harmen H.M., White Stefan J., Santen Gijs W.E., Chuva de Sousa Lopes Susana M., Heijmans Bastiaan T., van Meurs Joyce, Jansen Rick, Franke Lude, Kiełbasa Szymon M., den Dunnen Johan T., ‘t Hoen Peter A.C., Heijmans Bastiaan T., ’t Hoen Peter Ac, van Meurs Joyce, Boomsma Dorret I., Pool René, van Dongen Jenny, Hottenga Jouke J., van Greevenbroek Marleen Mj, Stehouwer Coen Da, van der Kallen Carla Jh, Schalkwijk Casper G., Wijmenga Cisca, Zhernakova Sasha, Tigchelaar Ettje F., Slagboom P. Eline, Beekman Marian, Deelen Joris, van Heemst Diana, Veldink Jh, van den Berg Leonard H., Deelen Patrick, Francioli Lc, Pulit Sl, Guryev V., Kloosterman Wp, Deelen Patrick, van Leeuwen Em, van Setten J., Nijman Ij, Renkens I., Veldink Jh, van den Berg Leonard H., Li Y., Wang J., de Bakker Pi, , 1 Mar 2019, In: European Journal of Human Genetics. 27 , p. 455-465 11 p.

Single-Molecule Sequencing:Towards Clinical Applications

Ameur Adam, Kloosterman Wigard P., Hestand Matthew S. 1 Jan 2019, In: Trends in biotechnology. 37 , p. 72-85 14 p.

Confirmation of a metastasis-specific microRNA signature in primary colon cancer

Coebergh Van Den Braak Robert R.J., Sieuwerts Anieta M., Lalmahomed Zarina S., Smid Marcel, Wilting Saskia M., Bril Sandra I., Xiang Shanshan, Van Der Vlugt-Daane Michelle, De Weerd Vanja, Van Galen Anne, Biermann Katharina, Van Krieken J. Han J.M., Kloosterman Wigard P., Foekens John A., Martens John W.M., Ijzermans Jan N.M., Coene Peter Paul L.O., Dekker Jan Willem T., Zimmerman David D.E., Tetteroo Geert W.M., Vles Wouter J., Vrijland Wietske W., 1 Dec 2018, In: Scientific Reports. 8

Enhancer hubs and loop collisions identified from single-allele topologies

Allahyar Amin, Vermeulen Carlo, Bouwman Britta A.M., Krijger Peter H.L., Verstegen Marjon J.A.M., Geeven Geert, van Kranenburg Melissa, Pieterse Mark, Straver Roy, Haarhuis Judith H.I., Jalink Kees, Teunissen Hans, Renkens Ivo J., Kloosterman Wigard P., Rowland Benjamin D., de Wit Elzo, de Ridder Jeroen, de Laat Wouter 1 Aug 2018, In: Nature Genetics. 50 , p. 1151-1160 10 p.

Mapping and phasing of structural variation in patient genomes using nanopore sequencing

Cretu Stancu Mircea, van Roosmalen Markus J, Renkens Ivo, Nieboer Marleen M, Middelkamp Sjors, de Ligt Joep, Pregno Giulia, Giachino Daniela, Mandrile Giorgia, Espejo Valle-Inclan Jose, Korzelius Jerome, de Bruijn Ewart, Cuppen Edwin, Talkowski Michael E., Marschall Tobias, de Ridder Jeroen, Kloosterman Wigard P 6 Nov 2017, In: Nature Communications [E]. 8

Ankyrin repeat and zinc-finger domain-containing 1 mutations are associated with infantile-onset inflammatory bowel disease

Van Haaften-Visser Désirée Y., Harakalova Magdalena, Mocholi Enric, Van Montfrans Joris M., Elkadri Abdul, Rieter Ester, Fiedler Karoline, Van Hasselt Peter M., Triffaux Emily M.M., Van Haelst Mieke M., Nijman Isaac J., Kloosterman Wigard P., Nieuwenhuis Edward E S , Muise Aleixo M., Cuppen Edwin, Houwen Roderick H.J., Coffer Paul J. 12 May 2017, In: Journal of Biological Chemistry. 292 , p. 7904-7920 17 p.

Defining the diverse spectrum of inversions, complex structural variation, and chromothripsis in the morbid human genome

Collins Ryan L, Brand Harrison, Redin Claire E., Hanscom Carrie, Antolik Caroline, Stone Matthew R, Glessner Joseph T., Mason Tamara, Pregno Giulia, Dorrani Naghmeh, Mandrile Giorgia, Giachino Daniela, Perrin Danielle, Walsh Cole, Cipicchio Michelle, Costello Maura, Stortchevoi Alexei, An Joon Yong, Currall Benjamin B, Seabra Catarina M, Ragavendran Ashok, Margolin Lauren, Martinez-Agosto Julian A., Lucente Diane, Levy Brynn, Sanders Jan-Stephan, Wapner Ronald J., Quintero-Rivera Fabiola, Kloosterman Wigard, Talkowski Michael E. 6 Mar 2017, In: Genome Biology. 18

Molecular dissection of germline chromothripsis in a developmental context using patient-derived iPS cells

Middelkamp Sjors, van Heesch S.A.A.C., Braat Koen, de Ligt J, van Iterson Maarten, Simonis Marieke, van Roosmalen Markus J. , Kelder Martijn J E, Kruisselbrink Evelien, Hochstenbach Ron, Verbeek Nienke, Ippel Elly, Adolfs Y., Pasterkamp R. Jeroen, Kloosterman Wigard P., Kuijk Ewart W., Cuppen Edwin 26 Jan 2017, In: Genome Medicine. 9

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