drs. S.T. (Dörte) Kruijf

drs. S.T. (Dörte) Kruijf

Full Professor
drs. S.T. (Dörte) Kruijf
  • Center for Translational Immunology (CTI) Research
  • Central Diagnostic Laboratory

Research Programs

Infection & Immunity



Dörte Hamann (1967) started her career in basic immunological research on phenotype and function of CD8+ T cells. As a post-doc she studied the effect of HIV infection on the immune system. Her interest in clinical research and patient diagnostics made her move towards laboratory medicine. Her present work focusses on implementation of new immunological insights into diagnostics and the integration of immunological diagnostics with other laboratory specialisms.

Dörte Hamann studied Biology at the University of Leipzig in Germany. After finishing her studies she moved to Amsterdam to work on her PhD project “Human T cells -phenotype and function” at the CLB (now Sanquin), Amsterdam. After working several years as a post-doc in HIV research at Sanquin, Amsterdam, she was trained as laboratory specialist Medical Immunology at Sanquin and the Academic Medical Center Amsterdam and got registered in 2007. At Sanquin Diagnostics she headed the Immunopathology and Blood Coagulation Department. Since 2018 she is responsible for the medical immunology diagnostics at the Utrecht University Medical Center and is heading the Advanced Diagnostics Laboratory of the Central Diagnostics Laboratory. In 2020 she became professor for integrated immunological diagnostics. She is the chairman of the board of the College of Medical Immunologists and an active member of the Dutch IVDR taskforce, in which she represents the College of Medical Immunologists.

Side Activities

2020-present     Chairman of the Sjögren’s Award commission of the Dutch Society of Sjögren Patients (NVSP)

2018-present     Chairman of the Board of the College of Medical Immunologists

2013-2018         Instructor Medical Immunology AMC-Sanquin

2012-2018         Member College of Medical Immunologists, Training and Registration Committee, since 2016 secretary

2010-2018         Member Scientific Advisory Board Jan van Bremen Institute

2010-2013         Member Scientific Advisory Board Dutch Arthritis Foundation

2009-2019         Member steering committee and treasurer European Autoimmune Standardization Initiative (EASI) working group Netherland

2009-2018         Secretary and treasurer Dutch Foundation for Quality Assessment in Medical Laboratories (SKML), section Humoral Immunity

2007-2013         Co-instructor Medical Immunology AMC-Sanquin

2004- present    Member steering committee European Consensus Finding Study Group on Autoantibodies in Rheumatic Diseases (within the European League Against Rheumatism (EULAR))

2003-2018         Instructor Foundation for the promotion and maintenance of a system of training programs for biomedical scientists (SMBWO)


Research Output (5)

Biomarkers of Checkpoint Inhibitor Induced Immune-Related Adverse Events-A Comprehensive Review

Hommes Josefien W, Verheijden Rik J, Suijkerbuijk Karijn P M, Hamann Dörte 11 Feb 2021, In: Frontiers in oncology. 10

The end of the laboratory developed test as we know it?:Recommendations from a national multidisciplinary taskforce of laboratory specialists on the interpretation of the IVDR and its complications

Bank Paul C D, Jacobs Leo H J, van den Berg Sjoerd A A, van Deutekom Hanneke W M, Hamann Dörte, Molenkamp Richard, Ruivenkamp Claudia A L, Swen Jesse J, Tops Bastiaan B J, Wamelink Mirjam M C, Wessels Els, Oosterhuis Wytze P 23 Nov 2020, In: Clinical Chemistry and Laboratory Medicine. 59 , p. 491-497 7 p.

Establishment of the CD4+ T-cell pool in healthy children and untreated children infected with HIV-1

Hazenberg Mette D, Otto Sanquin, van Rossum Annemarie M C, Scherpbier Henriëtte J, de Groot Ronald, Kuijpers Taco W, Lange Joep M A, Hamann Dörte, de Boer Rob J, Borghans José A M, Miedema Sanquin 1 Dec 2004, In: Blood. 104 , p. 3513-9 7 p.

Phenotypic and functional separation of memory and effector human CD8+ T cells

Hamann D, Baars P A, Rep M H, Hooibrink B, Kerkhof-Garde S R, Klein M R, van Lier R A 3 Nov 1997, In: Journal of Experimental Medicine. 186 , p. 1407-18 12 p.

CD30 expression does not discriminate between human Th1- and Th2-type T cells

Hamann D, Hilkens CMU, Grogan JL, Lens SMA, Kapsenberg ML, Yazdanbakhsh M, vanLier RAW 15 Feb 1996, In: Journal of Immunology. 156 , p. 1387-1391

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