prof. drs. F.G.G. (Mirjam) Huijer

prof. drs. F.G.G. (Mirjam) Huijer

Associate Professor
prof. drs. F.G.G. (Mirjam) Huijer
  • Department of Epidemiology
  • Julius Center Research Program Cardiovascular Epidemiology

Research Programs



I received my MSc degree in Neuropsychology and PhD degree in Epidemiology from the VU medical center Amsterdam, the Netherlands. From 2000 until 2002, I worked as a post-doc at the Department of Epidemiology & Biostatistics of the Erasmus Medical Center, Rotterdam where I studied steroid hormones as risk factors for dementia using data from the Rotterdam Study. Since 2002, I work at the Julius Center for Health Sciences and Primary Care (University Medical Center Utrecht). I initiate, conduct, and supervise research within the department of Epidemiology and develop, coordinate and teach epidemiology courses within the Biomedical Sciences (BSc), Medicine (BSc and MSc), and MSc Epidemiology curriculum. I supervised around 40 MSc and BSc students during their research and completing their MSc or BSc thesis. Additionally, I have mentored a substantial number of research assistants, PhD candidates, and postdoctoral fellows. I am a PI of the research programs Circulatory Health (research theme Cerebrovascular disease) and Brain within the UMC Utrecht. 

Within the UMC Utrecht, I lead the SMART-MR study, a sub-study of the UCC-SMART study. The SMART-MR study (SMART-MR study) is an ongoing prospective cohort study among 1309 non-demented, independently living middle-aged to older adults with manifest arterial disease, aimed to investigate determinants and consequences of brain changes on MRI, including depression and cognitive decline. Individuals were assessed at up to three visits: at baseline, 4 years, and 12 years follow-up. I am also PI of the Medea 7T study, a cohort study in the UMC Utrecht, aimed to investigate determinants and consequences of microstructural brain abnormalities on 7 tesla brain MRI. With the UCC-SMART study and SMART-MR study I participate in national and international consortia, including the Netherlands Consortium for Dementia Cohorts (NCDC), the Psychosocial factors and cancer incidence (PSY-CA) consortium, and the CHARGE consortium.

Internationally, I have longstanding collaborations with the Laboratory of Epidemiology and Population Sciences, National Institute on Aging, USA (dr. Lenore Launer) where I published using data from the Honolulu Asia Aging Study and the AGES-Reykjavik Study.


Research line

Epidemiology of cerebrovascular disease and brain health.



in PubMed:

geerlings mi OR (geerlings m AND (gerritsen OR nazareth)) OR (ggeerlings mi AND Scarth M AND Vonk JM AND Gerritsen L) - Search Results - PubMed (


Side Activities


Chair or vice-chair

2019                 Chair of the Talma Eykman Master’s Thesis Awards committee (University Medical Center Utrecht).

2014–2017        Chair of the Veni ZonMw programme committee (Innovational Research Incentives Scheme) of The Netherlands Organisation for Scientific Research (NWO).

2013                 Vice-chair of the Veni ZonMw programme committee (Innovational Research Incentives Scheme) of The Netherlands Organisation for Scientific Research (NWO).



2021-2022         Member of the ZonMw Off Road committee.

2021-2022     Substitute methodological member of the Institutional Review Board (Independent Ethics Committee) of the University Medical Center Utrecht.

2018                 Member of the Talma Eykman Master’s Thesis Awards committee (University Medical Center Utrecht).

2017-present     Member of the Alzheimer Nederland fellowship grant programme committee.

2016-present     Member of the examiner board of the curriculum Medicine (Examencommissie Geneeskunde) (University Medical Center Utrecht).

2014                 Member of the Earth and Life Sciences Open Programme committee (ALW-Open programma) of The Netherlands Organisation for Scientific Research (NWO).

2011                 Member of the Veni ZonMw programme committee (Innovational Research Incentives Scheme) of The Netherlands Organisation for Scientific Research (NWO).

2011-2017         Substitute methodological member of the Institutional Review Board (Independent Ethics Committee) of the University Medical Center Utrecht.

2007-2011         Methodological member of the Institutional Review Board (Independent Ethics Committee) of the University Medical Center Utrecht.


Society memberships

2016-present                 Member of the sounding board of the Dutch Network of Women Professors (klankbordgroep UHD Landelijk Netwerk Vrouwelijke Hoogleraren)

2012-present                 Dutch Network of Women Professors (Landelijk Netwerk Vrouwelijke Hoogleraren)

2009-present                International Society to Advance Alzheimer Research and Treatment (ISTAART)

2007-present                International Society for Vascular, Cognitive and Behavioural Disorders (VasCog)

Research Output (226)

Microinfarcts in the Deep Gray Matter on 7T MRI:Risk Factors, MRI Correlates, and Relation to Cognitive Functioning-The SMART-MR Study

Ghaznawi R, Zwartbol M H T, de Bresser J, Kuijf H J, Vincken K L, Rissanen I, Geerlings M I, Hendrikse J, 26 May 2022, In: AJNR. American journal of neuroradiology. 43 , p. 829-836 8 p.

Automatic quantification of perivascular spaces in T2-weighted images at 7 T MRI

Verbeek-Spijkerman Jolanda, Zwanenburg J. J.M., Bouvy W. H., Geerlings M. I., Biessels G. J., Hendrikse J., Luijten P. R., Kuijf H. J. 13 Apr 2022, In: Cerebral Circulation - Cognition and Behavior. 3 , p. 1-9

Chronic neuropsychiatric sequelae of SARS-CoV-2:Protocol and methods from the Alzheimer's Association Global Consortium

de Erausquin Gabriel A et al. 2022, In: Alzheimer's and Dementia: Translational Research and Clinical Interventions. 8 , p. e12348

Depression and Dementia:The Role of Cortisol and Vascular Brain Lesions. AGES-Reykjavik Study

Gerritsen Lotte, Twait Emma L, Jonsson Palmi V, Gudnason Vilmundur, Launer Lenore J, Geerlings Mirjam I 21 Dec 2021, In: Journal of Alzheimer's Disease. 85 , p. 1677-1687 11 p.

Predictors of Incident Mild Cognitive Impairment and Its Course in a Diverse Community-Based Population

Angevaare Milou J, Vonk Jet M J, Bertola Laiss, Zahodne Laura, Wei-Ming Watson Caitlin, Boehme Amelia, Schupf Nicole, Mayeux Richard, Geerlings Mirjam I, Manly Jennifer J 1 Dec 2021, In: Neurology. 98 , p. E15-E26

An anomaly detection approach to identify chronic brain infarcts on MRI

van Hespen Kees M, Zwanenburg Jaco J M, Dankbaar Jan W, Geerlings Mirjam I, Hendrikse Jeroen, Kuijf Hugo J Dec 2021, In: Scientific Reports. 11

Psychosocial factors and cancer incidence (PSY-CA):Protocol for individual participant data meta-analyses

van Tuijl Lonneke A., Voogd Adri C., de Graeff Alexander, Hoogendoorn Adriaan W., Ranchor Adelita V., Pan Kuan Yu, Basten Maartje, Lamers Femke, Geerlings Mirjam I., Abell Jessica G., Awadalla Philip, Bakker Marije F., Beekman Aartjan T.F., Bjerkeset Ottar, Boyd Andy, Cui Yunsong, Galenkamp Henrike, Garssen Bert, Hellingman Sean, Huisman Martijn, Huss Anke, Keats Melanie R., Kok Almar A.L., Luik Annemarie I., Noisel Nolwenn, Onland-Moret N. Charlotte, Payette Yves, Penninx Brenda W.J.H., Portengen Lützen, Rissanen Ina, Roest Annelieke M., Rosmalen Judith G.M., Ruiter Rikje, Schoevers Robert A., Soave David M., Spaan Mandy, Steptoe Andrew, Stronks Karien, Sund Erik R., Sweeney Ellen, Teyhan Alison, Vaartjes Ilonca, van der Willik Kimberly D., van Leeuwen Flora E., van Petersen Rutger, Verschuren W. M.Monique, Visseren Frank, Vermeulen Roel, Dekker Joost 2 Sep 2021, In: Brain and Behavior. 11 , p. 1-13

Biomarkers of Alzheimer's Disease and Cerebrovascular Lesions and Clinical Progression in Patients with Subjective Cognitive Decline:A Systematic Review

Scarth Morgan, Rissanen Ina, Scholten Rob J P M, Geerlings Mirjam I 13 Aug 2021, In: Journal of Alzheimer's Disease. 83 , p. 1089-1111 23 p.

Cross-sectional associations of tau protein biomarkers with semantic and episodic memory in older adults without dementia:A systematic review and meta-analysis

Pelgrim Teuntje A D, Beran Magdalena, Twait Emma L, Geerlings Mirjam I, Vonk Jet M J 13 Aug 2021, In: Ageing Research Reviews. 71

Association of Ischemic Imaging Phenotype With Progression of Brain Atrophy and Cerebrovascular Lesions on MRI:The SMART-MR Study

Rissanen Ina, Lucci Carlo, Ghaznawi Rashid, Hendrikse Jeroen, Kappelle L. Jaap, Geerlings Mirjam I., , van der Kaaij NP, Asselbergs Folkert 21 Jul 2021, In: Neurology. 97 , p. e1063-e1074

All research output

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