dr. Z.A. (Roel) Hoogen

dr. Z.A. (Roel) Hoogen

Full Professor
dr. Z.A. (Roel) Hoogen
  • Department of Pathology

Research Programs

Circulatory Health

Side Activities

From this activity for the UMC Utrecht there is no personal income.


Fibrogen Inc., San Francisco, CA: 94348 Euro vergoeding laboratoriumkosten (“Fee for service contract”) voor onderzoek naar de rol van galectine-3 in experimentele leverfibrose.

Research Output (237)

CCN2 Aggravates the Immediate Oxidative Stress–DNA Damage Response following Renal Ischemia–Reperfusion Injury

Valentijn Floris, Goldschmeding Roel, Marquez Exposito Laura, Broekhuizen R., Nguyen Tri Q., Knoppert Sebastiaan, Falke LL, Kester Lennart, Mokry Michal, Ruiz-Ortega Marta, Rodrigues-Diez Raúl R. 20 Dec 2021, In: Antioxidants. 10 , p. 1-16

Connective Tissue Growth Factor Single Nucleotide Polymorphisms in (Familial) Pulmonary Fibrosis and Connective Tissue Disease Associated Interstitial Lung Disease

Klay Dymph, van der Vis Joanne J., Roothaan Suzan M., Nguyen Tri Q., Grutters Jan C., Goldschmeding Roel, van Moorsel Coline H.M. Dec 2021, In: Lung. 199 , p. 659-666 8 p.

Pulmonary fibrosis in non-mutation carriers of families with short telomere syndrome gene mutations

van der Vis Joanne J., van der Smagt Jasper J., van Batenburg Aernoud A., Goldschmeding Roel, van Es H. Wouter, Grutters Jan C., van Moorsel Coline H.M. Dec 2021, In: Respirology. 26 , p. 1160-1170 11 p.

The Extent of Inflammatory Cell Infiltrate and Fibrosis in Lungs of Telomere- and Surfactant-Related Familial Pulmonary Fibrosis

van Batenburg Aernoud A., van Oosterhout Matthijs F.M., Knoppert Sebastiaan N., Kazemier Karin M., van der Vis Joanne J., Grutters Jan C., Goldschmeding Roel, van Moorsel Coline H.M. 24 Sep 2021, In: Frontiers in medicine. 8 , p. 1-10

Interplay between extracellular matrix components and cellular and molecular mechanisms in kidney fibrosis

Rayego-Mateos Sandra, Campillo Sofia, Rodrigues-Diez Raúl R., Tejera-Muñoz Antonio, Marquez-Exposito Laura, Goldschmeding Roel, Rodríguez-Puyol Diego, Calleros Laura, Ruiz-Ortega Marta Aug 2021, In: Clinical Science. 135 , p. 1999-2029 31 p.

PAI-1 induction during kidney injury promotes fibrotic epithelial dysfunction via deregulation of klotho, p53, and TGF-beta 1-receptor signaling

Gifford Cody C., Lian Fei, Tang Jiaqi, Costello Angelica, Goldschmeding Roel, Samarakoon Rohan, Higgins Paul J. Jul 2021, In: FASEB Journal. 35 , p. 1-17

Acute Kidney Injury is Aggravated in Aged Mice by the Exacerbation of Proinflammatory Processes

Marquez-Exposito Laura, Tejedor-Santamaria Lucia, Santos-Sanchez Laura, Valentijn Floris A., Cantero-Navarro Elena, Rayego-Mateos Sandra, Rodrigues-Diez Raul R., Tejera-Muñoz Antonio, Marchant Vanessa, Sanz Ana B., Ortiz Alberto, Goldschmeding Roel, Ruiz-Ortega Marta 22 Jun 2021, In: Frontiers in Pharmacology. 12 , p. 1-19

Extracellular Granzyme K Modulates Angiogenesis by Regulating Soluble VEGFR1 Release From Endothelial Cells

Li Shuang, van Dijk Christian G.M., Meeldijk Jan, Kok Helena M., Blommestein Isabelle, Verbakel Annick L.F., Kotte Marit, Broekhuizen Roel, Laclé Miangela M., Goldschmeding Roel, Cheng Caroline, Bovenschen Niels 9 Jun 2021, In: Frontiers in oncology. 11 , p. 1-11

Connective Tissue Growth Factor Is Overexpressed in Explant Lung Tissue and Broncho-Alveolar Lavage in Transplant-Related Pulmonary Fibrosis

Vanstapel Arno, Goldschmeding Roel, Broekhuizen Roel, Nguyen Tri, Sacreas Annelore, Kaes Janne, Heigl Tobias, Verleden Stijn E., De Zutter Alexandra, Verleden Geert, Weynand Birgit, Verbeken Erik, Ceulemans Laurens J., Van Raemdonck Dirk E., Neyrinck Arne P., Schoemans Helene M., Vanaudenaerde Bart M., Vos Robin 25 May 2021, In: Frontiers in Immunology. 12 , p. 1-14

P62-positive aggregates are homogenously distributed in the myocardium and associated with the type of mutation in genetic cardiomyopathy

van der Klooster Zoë Joy, Sepehrkhouy Shahrzad, Dooijes Dennis, Te Rijdt Wouter P, Schuiringa Frederique S A M, Lingeman Jolanthe, van Tintelen Johannes Peter, Harakalova Magdalena, Goldschmeding Roel, Suurmeijer Albert J H, Asselbergs Folkert W, Vink Aryan 18 Feb 2021, In: Journal of Cellular and Molecular Medicine. 25 , p. 3160-3166 7 p.

All research output

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