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drs. P. (Stefano) Heinhuis

drs. P. (Stefano) Heinhuis

Assistant Professor
drs. P. (Stefano) Heinhuis
  • Computational Imaging

Research Programs

Strategic Program Cancer

Biography

Biography

Stefano is currently employed as assistant professor at the radiotherapy department of the University Medical Center Utrecht (The Netherlands). His research topics range from fundamental and methodological research to clinical development of quantitative MRI methods and MRI biomarkers for diagnostic and radiotherapy treatment response prediction and monitoring. In particular, he works on the characterization of tissue electrical properties for radiotherapy treatments efficacy assessment using MRI (NWO recipient VENI grant 2020), MRI-guided cardiac radio-ablation using stereotactic radiotherapy (STOPSTORM.eu consortium), MRI-based guidance of spinal cord stimulation (RESTORE and Prep2GO consortia), and he also supports the development and translation of quantitative MRI methods in clinical settings (MR-STAT).

Background

Stefano was born in Camposampiero, Padua (Italy) in September 1988. He was educated as a bioengineer at the University of Padua, 2007-2013. Afterwards, he moved to The Netherlands where he received his Ph.D. in the field of non-invasive characterization of tissue electrical properties with MRI at the University Medical Center Utrecht (The Netherlands) in 2018. Subsequently, he was offered a Post-Doc position at the Radiology and Radiotherapy departments of the University Medical Center Utrecht. Because of his passion for MRI and his positive attitude, which makes him looking at research challenges as new opportunities to expand his knowledge and to establish new collaborations, he also recently started investigating MRI-based guidance of cardiac ablation using stereotactic radiotherapy at the radiotherapy department of the University Medical Center Utrecht within the European STOPSTORM consortium.

Fellowship and Awards

NWO VENI Grant (2020): MR-based measurements of ‘Tissue ElectroMagnetic Properties in radiation Oncology (TEMPO)’: A predictive tool for early-stage assessment of radiotherapy treatments

Junior Fellow of the International Society for Magnetic Resonance in Medicine, ISMRM (2020)

Trainee Educational Stipend of the International Society for Magnetic Resonance in Medicine, ISMRM (2014, 2015, 2016)

Research Output (33)

Acceleration Strategies for MR-STAT: Achieving High-Resolution Reconstructions on a Desktop PC Within 3 Minutes

Liu Hongyan, van der Heide Oscar, Mandija Stefano, van den Berg Cornelis A. T., Sbrizzi Alessandro Oct 2022, In: IEEE transactions on medical imaging. 41 , p. 2681-2692

Dynamic Contrast-enhanced and Diffusion-weighted Magnetic Resonance Imaging for Response Evaluation After Single-Dose Ablative Neoadjuvant Partial Breast Irradiation

Vasmel Jeanine E., Groot Koerkamp Maureen L., Mandija Stefano, Veldhuis Wouter B., Moman Maaike R., Froeling Martijn, van der Velden Bas H.M., Charaghvandi Ramona K., Vreuls Celien P.H., van Diest Paul J., van Leeuwen A. M.Gijs, van Gorp Joost, Philippens Marielle E.P., van Asselen Bram, Lagendijk Jan J.W., Verkooijen Helena M., van den Bongard H. J.G.Desirée, Houweling Antonetta C. 1 Mar 2022, In: Advances in Radiation Oncology. 7 , p. 1-11

First experimental exploration of real-time cardiorespiratory motion management for future stereotactic arrhythmia radioablation treatments on the MR-linac

Akdag Osman, Borman Pim T S, Woodhead Peter L, Uijtewaal Prescilla, Mandija Stefano, van Asselen Bram, Verhoeff Joost J C, Raaymakers Bas W, Fast Martin F 21 Feb 2022, In: Physics in medicine and biology. 67 , p. 1-14

Feasibility of cardiac-synchronized quantitative T1 and T2 mapping on a hybrid 1.5 Tesla magnetic resonance imaging and linear accelerator system

Akdag Osman, Mandija Stefano, van Lier Astrid L H M W, Borman PTS, Schakel Tim, Alberts Eveline, van der Heide Oscar, Hassink Rutger J, Verhoeff Joost J C, Mohamed Hoesein Firdaus A A, Raaymakers Bas W, Fast Martin F Jan 2022, In: Physics and Imaging in Radiation Oncology. 21 , p. 153-159 7 p.

Prone vs. supine accelerated partial breast irradiation on an MR-Linac:A planning study

Groot Koerkamp Maureen L., van der Leij Femke, van 't Westeinde Tanja, Bol Gijsbert H., Scholten Vincent, Bouwmans Roel, Mandija Stefano, Philippens Marielle E.P., van den Bongard H. J.G.Desirée, Houweling Antonetta C. Dec 2021, In: Radiotherapy and Oncology. 165 , p. 193-199 7 p.

Cardiac-Synchronized T1 mapping on the Unity MR-linac to guide STereotactic Arrhythmia Radioablation

Mandija S., Akdag O., van Lier A., Borman P., Schakel T., Alberts E., van der Heide O., Hassink R., Alings M., Verhoeff J., Mohamed Hoesein F., Fast M. Aug 2021, In: Radiotherapy and Oncology. 161 , p. S408-S409

Left-ventricular MRI navigation: a novel approach for motion-free thoracic and cardiac radiotherapy

van Lier A., Akdag O., Mandija S., Borman P., Alberts E., Fast M. Aug 2021, In: Radiotherapy and Oncology. 161 , p. S517-S518

Improving phase-based conductivity reconstruction by means of deep learning-based denoising of B 1 + phase data for 3T MRI

Jung Kyu-Jin, Mandija Stefano, Kim Jun-Hyeong, Ryu Kanghyun, Jung Soozy, Cui Chuanjiang, Kim Soo-Yeon, Park Mina, van den Berg Cornelis A T, Kim Dong-Hyun 5 May 2021, In: Magnetic Resonance in Medicine. 86 , p. 2084-2094 11 p.

Synthetic CT for single-fraction neoadjuvant partial breast irradiation on an MRI-linac

Groot Koerkamp Maureen L, de Hond Yvonne J M, Maspero Matteo, Kontaxis Charis, Mandija Stefano, Vasmel Jeanine E, Charaghvandi Ramona K, Philippens Marielle E P, van Asselen Bram, van den Bongard H J G Desirée, Hackett Sara S, Houweling Antonetta Christina 24 Mar 2021, In: Physics in medicine and biology. 66

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