mr. dr. K.L. (Caroline) Edelenbos

mr. dr. K.L. (Caroline) Edelenbos

Assistant Professor - medical
mr. dr. K.L. (Caroline) Edelenbos
  • SCT patient care



Caroline Lindemans, MD, PhD is a pediatrician, BMT specialist  and pediatric immunologist in the UMC Utrecht. Appointed as a consultant in HCT she has a special  research interest in graft versus host disease, intestinal toxicity, it’s prevention and therapy.  After receiving a KWF fellowship grant she recently worked at Memorial Sloan Kettering Cancer Center in the Research groups of Marcel van den Brink  and Alan Hanash resulting in a first author Nature paper, published December 2015. She has ongoing collaborations with these groups and is currently expanding this line of research in the UMC Utrecht.  Caroline is an active member of various international working committees (e.g. EBMT, CIBMTR: chair of one of the CIBMTR working committees).

Side Activities

  • Co-chair CIBMTR working committee Infection and Immunity February 2014—Feb 2017
  • Medical Consultant Chimerix europe (Brincidofovir studies): 2015-heden

Fellowship and Awards

  • 2000 Wilhelmina Children's Hospital Student Research Prize
  • 2010 ASBMT Travel grant for young investigators $500
  • 2012 Abstract award winner international cord blood symposium
  • 2012 UMC Utrecht mobilization grant  €20.000 euro
  • 2013 Wilhelmina Children’s hospital Fund: Leading ladies  research stimulation grant €125.000 euro
  • 2013 Travel Stipendium Nijbakker Morra Foundation €9.600 euro
  • 2013 KWF (Dutch Cancer Society) Clinical fellowship Grant €250.000 euro. To study tissue regeneratation in GVHD.
  • 2014 ASH Abstract Achievement Award

Research Output (97)

Naive T Cells in Graft Versus Host Disease and Graft Versus Leukemia:Innocent or Guilty?

Dekker Linde, Sanders Evy, Lindemans Caroline A., de Koning Coco, Nierkens Stefan 20 Jun 2022, In: Frontiers in Immunology. 13 , p. 1-10

Fludarabine exposure predicts outcome after CD19 CAR T-cell therapy in children and young adults with acute leukemia

Dekker Linde, Calkoen Friso G., Jiang Yilin, Blok Hilly, Veldkamp Saskia R., De Koning Coco, Spoon Maike, Admiraal Rick, Hoogerbrugge Peter, Vormoor Britta, Vormoor H. Josef, Visscher Henk, Bierings Marc, Van Der Vlugt Marieke, Van Tinteren Harm, Nijstad A. Laura, Huitema Alwin D.R., Van Der Elst Kim C.M., Pieters Rob, Lindemans Caroline A., Nierkens Stefan 12 Apr 2022, In: Blood Advances. 6 , p. 1969-1976 8 p.

Therapeutic Drug Monitoring of Anti-Thymocyte Globulin in Allogeneic Stem Cell Transplantation:Proof of Concept

Meesters-Ensing J I, Admiraal R, Ebskamp L, Lacna A, Boelens J J, Lindemans C A, Nierkens S 18 Mar 2022, In: Frontiers in Pharmacology. 13 , p. 1-8

Modified Delphi procedure-based expert consensus on endpoints for an international disease registry for Metachromatic Leukodystrophy:The European Metachromatic Leukodystrophy initiative (MLDi)

Schoenmakers Daphne H., Beerepoot Shanice, van den Berg Sibren, Adang Laura, Bley Annette, Boelens Jaap Jan, Fumagalli Francesca, Goettsch Wim G., Grønborg Sabine, Groeschel Samuel, van Hasselt Peter M., Hollak Carla E.M., Lindemans Caroline, Mochel Fanny, Mol Peter G.M., Sevin Caroline, Zerem Ayelet, Schöls Ludger, Wolf Nicole I. 14 Feb 2022, In: Orphanet Journal of Rare Diseases. 17

Lymphoid and myeloid immune cell reconstitution after nicotinamide-expanded cord blood transplantation

de Koning Coco, Tao Weiyang, Lacna Amelia, van Veghel Karin, Horwitz Mitchell E., Sanz Guillermo, Jagasia Madan H., Wagner John E., Stiff Patrick J., Hanna Rabi, Cilloni Daniela, Valcárcel David, Peled Tony, Galamidi Cohen Einat, Goshen Uri, Pandit Aridaman, Lindemans Caroline A., Jan Boelens Jaap, Nierkens Stefan Nov 2021, In: Bone Marrow Transplantation. 56 , p. 2826-2833 8 p.

KIR3DS1 directs NK cell-mediated protection against human adenovirus infections

Jung Johannes M, Ching Wilhelm, Baumdick Martin E, Hofmann-Sieber Helga, Bosse Jens B, Koyro Tobias, Möller Kimberly J, Wegner Lucy, Niehrs Annika, Russu Kristina, Ohms Mareike, Zhang Wenli, Ehrhardt Anja, Duisters Kevin, Spierings Eric, Hölzemer Angelique, Körner Christian, Jansen Suze A, Peine Sven, Königs Ingo, Lütgehetmann Marc, Perez Daniel, Reinshagen Konrad, Lindemans Caroline A, Altfeld Marcus, Belderbos Mirjam, Dobner Thomas, Bunders Madeleine J 17 Sep 2021, In: Science Immunology. 6 , p. 1-13 14 p.

Allogenic Hematopoietic Stem Cell Transplantation Is Feasible in Pediatric Patients with an Active or Recently Diagnosed Invasive Fungal Infection

Rotte Laura G.Y., Loeffen Yvette G.T., Bierings Marc B., Wolfs Tom F.W., Lindemans Caroline A. Sep 2021, In: Transplantation and Cellular Therapy. 27 , p. 781.e1-781.e5

Long-term effect of hematopoietic cell transplantation on systemic inflammation in patients with mucopolysaccharidoses

van den Broek Brigitte T A, Lindemans Caroline A, Boelens Jaap Jan, Delemarre Eveline M, Drylewicz Julia, Verhoeven-Duif Nanda, van Hasselt Peter M, Nierkens Stefan 24 Aug 2021, In: Blood Advances. 5 , p. 3092-3101 10 p.

Neurofilament light chain and glial fibrillary acidic protein levels in metachromatic leukodystrophy

Beerepoot Shanice, Heijst Hans, Roos Birthe, Wamelink Mirjam M C, Boelens Jaap Jan, Lindemans Caroline A, van Hasselt Peter M, Jacobs Edwin H, van der Knaap Marjo S, Teunissen Charlotte E, Wolf Nicole I 16 Aug 2021, In: Brain : a journal of neurology. 145 , p. 105-118 14 p.

Hematopoietic dysfunction during graft-versus-host disease:A self-destructive process?

Müskens Konradin F., Lindemans Caroline A., Belderbos Mirjam E. 10 Aug 2021, In: Cells. 10 , p. 1-17

All research output

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