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prof. dr. C.D.D. (Wouter) de Mackaaij

prof. dr. C.D.D. (Wouter) de Mackaaij

Full Professor

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Research Output (86)

Small chromosomal regions position themselves autonomously according to their chromatin class

Van De Werken Harmen J.G., Haan Josien C., Feodorova Yana, Bijos Dominika, Weuts An, Theunis Koen, Holwerda Sjoerd J.B., Meuleman Wouter, Pagie Ludo, Thanisch Katharina, Kumar Parveen, Leonhardt Heinrich, Marynen Peter, van Steensel Bas, Voet Thierry, De Laat Wouter, Solovei Irina, Joffe Boris 1 Jun 2017, In: Genome Research. 27 , p. 922-933 12 p.

Can We Just Say:Transcription Second?

Krijger Peter Hugo Lodewijk, de Laat Wouter 6 Apr 2017, In: Cell. 169 , p. 184-185 2 p.

Enhancer-Mediated Oncogenic Function of the Menin Tumor Suppressor in Breast Cancer

Dreijerink Koen M A, Groner Anna C., Vos Erica S M, Font-Tello Alba, Gu Lei, Chi David, Reyes Jaime, Cook Jennifer, Lim Elgene, Lin Charles Y., de Laat Wouter, Rao Prakash K., Long Henry W., Brown Myles 7 Mar 2017, In: Cell Reports [E]. 18 , p. 2359-2372 14 p.

Sensitive Monogenic Noninvasive Prenatal Diagnosis by Targeted Haplotyping

Vermeulen Carlo, Geeven Geert, de Wit Elzo, Verstegen Marjon J A M, Jansen Rumo P.M., van Kranenburg Melissa, de Bruijn Ewart, Pulit Sara L., Kruisselbrink Evelien, Shahsavari Zahra, Omrani Davood, Zeinali Fatemeh, Najmabadi Hossein, Katsila Theodora, Vrettou Christina, Patrinos George P., Traeger-Synodinos Joanne, Splinter Erik, Beekman Jeffrey M., Kheradmand Kia Sima, Te Meerman Gerard J, Ploos van Amstel Hans Kristian, de Laat Wouter 2017, In: American Journal of Human Genetics. 101 , p. 326-339

Regulation of disease-associated gene expression in the 3D genome

Krijger Peter Hugo Lodewijk, De Laat Wouter 21 Nov 2016, In: Nature reviews molecular cell biology. 17 , p. 771-782 12 p.

Enhancers reside in a unique epigenetic environment during early zebrafish development

Kaaij Lucas J T, Mokry Michal, Zhou Meng, Musheev Michael, Geeven Geert, Melquiond Adrien S J, de Jesus Domingues António M., de Laat Wouter, Niehrs Christof, Smith Andrew D., Ketting René F. 5 Jul 2016, In: Genome Biology. 17

The second decade of 3C technologies:Detailed insights into nuclear organization

Denker Annette, De Laat Wouter 15 Jun 2016, In: Genes and Development. 30 , p. 1357-1382 26 p.

Discovery and validation of sub-threshold genome-wide association study loci using epigenomic signatures

Wang Xinchen, Tucker Nathan R., Rizki Gizem, Mills Robert, Krijger Peter Hugo Lodewijk, de Wit Elzo, Subramanian Vidya, Bartell Eric, Nguyen Xinh Xinh, Ye Jiangchuan, Leyton-Mange Jordan, Dolmatova Elena V., Harst Pim Van Der, Laat Wouter De, Ellinor Patrick T., Newton-Cheh Christopher, Milan David J., Kellis Manolis, Boyer Laurie A. 10 May 2016, In: eLife. 2016

Cell-of-origin-specific 3D genome structure acquired during somatic cell reprogramming

Krijger Peter Hugo Lodewijk, Di Stefano Bruno, de Wit Elzo, Limone Francesco, Van Oevelen Chris, De Laat Wouter, Graf Thomas 5 May 2016, In: Cell Stem Cell. 18 , p. 597-610 14 p.

Epigenomic annotation of gene regulatory alterations during evolution of the primate brain

Vermunt Marit W., Tan Sander C., Castelijns Bas, Geeven Geert, Reinink Peter, de Bruijn Ewart, Kondova Ivanela, Persengiev Stephan, Bontrop Ronald, Cuppen Edwin, de laat Wouter, Creyghton Menno P., Mar 2016, In: Nature Neuroscience. 19 , p. 494-503 13 p.

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