drs. W.X.X. (Hugo) de Karssen

drs. W.X.X. (Hugo) de Karssen

Full Professor
drs. W.X.X. (Hugo) de Karssen
  • Medical Physics Group

Research Programs



Hugo de Jong completed his study (applied) physics in 1997 at the Eindhoven University of Technology with a thesis on quantitative measurement of atherosclerosis with MRI.  At the UMCU he defended his PhD-thesis on quantitative SPECT reconstruction under supervision of Freek Beekman and Max Viergever. Next was trained as medical physicist in the field of nuclear medicine and later appointed as staff member at the Amsterdam PET-Center (VUmc). In 2006 he started as the Medical Physics group leader for the department of Radiology and initiated a Medical Physics residency program. In addition he set up research lines in the field of CT and x-ray radiology, nuclear medicine physics and hybrid imaging. He was awarded with a personal VIDI grant and an ERC Consolidator Grant. In 2018 he was appointed professor in the field of Medical Physics Radiology and Nuclear Medicine.

Primary Interests: Physics of medical imaging, Teaching and Innovation.  Trainer of Medical Physics Residents.

Research grants:

  • ERC Proof of Concept ‘InSPECT’
  • NWO take-off grant
  • Leading the Change Zorgevaluatie, ‘Cleopatra’
  • TKI/Health Holland, ‘PET/MRI for guidance’
  • STW-Dutch Heart Foundation, ‘ENCLOSE’
  • ERC Consolidator Grant ‘IXSI3D’
  • ITEA2 Benefit, X-ray Intervention
  • ERC Proof of Concept, ‘MammoMedipix’
  • STW Carisma Airspace, Advanced CT perfusion Methods
  • ITEA2 Mediate, X-ray Interventions
  • Siemens Health Care research grant ‘Ready to go’

Side Activities

Member of Board of Review for Medical Physics Education (College van Toetsing NVKF)

Member of the ‘Commissie Buitenslands Gediplomeerden Volksgezondheid’ (ministerie VWS)

Member of the EFOMP-EANM committee core curriculum update for Medical Physics Experts working in Nuclear Medicine

Member of Board Dutch Society of Nuclear Medicine (bestuurslid Ned.Ver.Nucleaire Geneeskunde)

Member of the NVKF  committee on allocation of residencies (WGTO NVKF)

Research Output (149)

166Holmium–99mTechnetium dual‑isotope imaging: scatter compensation and automatic healthy‑liver segmentation for 166Holmium radioembolization dosimetry

Stella M, Braat Arthur, Lam Marnix, de Jong Hugo, van Rooij Rob 21 Apr 2022, In: EJNMMI Physics. 9 , p. 1-17

Beyond the MAA-Y90 Paradigm: The Evolution of Radioembolization Dosimetry Approaches and Scout Particles

Keane Grace, Lam Marnix, de Jong Hugo Dec 2021, In: Seminars in Interventional Radiology. 38 , p. 542-553 12 p.

Non-contrast dual-energy CT virtual ischemia maps accurately estimate ischemic core size in large-vessel occlusive stroke

Wolman Dylan N., van Ommen Fasco, Tong Elizabeth, Kauw Frans, Dankbaar Jan Willem, Bennink E, de Jong Hugo, Molvin Lior, Wintermark Max, Heit Jeremy J Dec 2021, In: Scientific Reports. 11

The Impact of Diferent 99mTc Activities on Dual Isotope Imaging for 166Holmium Scout Radioembolization Procedure

Stella M, Braat Arthur, Lam Marnix, de Jong Hugo, van Rooij Rob Sep 2021, p. S226

Correction to:Variability in lutetium-177 SPECT quantification between different state-of-the-art SPECT/CT systems

Peters Steffie M B, Meyer Viol Sebastiaan L, van der Werf Niels R, de Jong Nick, van Velden Floris H P, Meeuwis Antoi, Konijnenberg Mark W, Gotthardt Martin, de Jong Hugo W A M, Segbers Marcel 18 Aug 2021, In: EJNMMI physics. 8 3 p.

Evaluation of the radiofrequency performance of a wide-bore 1.5 T positron emission tomography/magnetic resonance imaging body coil for radiotherapy planning

Branderhorst Woutjan, Steensma Bart R., Beijst Casper, Huijing Erik R., Alborahal Cezar, Versteeg Edwin, Weissler Bjoern, Schug David, Gebhardt Pierre, Gross-Weege Nicolas, Mueller Florian, Krueger Karl, Dey Thomas, Radermacher Harald, Lips Oliver, Lagendijk Jan, Schulz Volkmar, de Jong Hugo W.A.M., Klomp Dennis W.J. Apr 2021, In: Physics and Imaging in Radiation Oncology. 17 , p. 13-19 7 p.

Gamma camera characterization at high holmium-166 activity in liver radioembolization

Stella M, Braat Arthur, Lam Marnix, de Jong Hugo, van Rooij Rob 2 Mar 2021, In: EJNMMI Phys. 8

Interventional respiratory motion compensation by simultaneous fluoroscopic and nuclear imaging:a phantom study

Dietze Martijn M A, Kunnen Britt, Lam Marnix G E H, de Jong Hugo W A M 11 Feb 2021, In: Physics in medicine and biology. 66

Current Status and Future Direction of Hepatic Radioembolisation

Alsultan A A, Braat A J A T, Smits M L J, Barentsz M W, Bastiaannet R, Bruijnen R C G, de Keizer B, de Jong H W A M, Lam M G E H, Maccauro M, Chiesa C Feb 2021, In: Clinical Oncology. 33 , p. 106-116 11 p.

All research output

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