prof. dr. A.L. (A.L.) Bredenoord

prof. dr. A.L. (A.L.) Bredenoord

Full Professor
prof. dr. A.L. (A.L.) Bredenoord
  • Department of Public Health, Healthcare Innovation & Evaluation and Medical Humanities (PHM)
  • Julius Center Research Program Methodology



Prof dr Annelien Bredenoord is a professor of Ethics of Biomedical Innovation at the University Medical Center Utrecht. Her research, consultancy and teaching is focused on the ethical issues in emerging biomedical technology and translational medicine.

She is particularly fascinated by the rapid developments in genetics/genomics, regenerative medicine, stem cell research, biobanking, surgical innovation, Big Data and the associated ethical and societal challenges: how to translate biomedical innovations from basic research into clinical care and society in an ethically sound way?

She published widely in those fields and is member of several (inter)national committees among which the Ethics Committee of the International Society for Stem Cell Research (ISSCR), The Young Academy of the Royal Netherlands Academy of Arts and Sciences (KNAW), The Young Health Council, The National Indication Committee Preimplantation Genetic Diagnosis, The NIAS Lorenz Advisory Board, L 'Oreal UNESCO For Women in Science program, and UMC Utrecht’s Research Ethics Committee (METC).

She obtained a VENI grant to study the ethics of translational stem cell research and supervises several PhD-students and medical students. She teaches ethics at the Medical School of Utrecht University.

Annelien has been political active for the Dutch social-liberal party D66 for 15 years. As of 2015, she is member of the Dutch Senate (Eerste Kamer) on behalf of D66.

Side Activities

- International Society for Stem Cell Research (ISSCR): Chair of the Ethics Committee (2016 - ongoing)      

-    International Stem Cell Forum (ISCF): Ethics Working Party (2011 - ongoing)

-          European Meeting on Psycho-Social Aspects of Genetics (EMPAG): Scientific Board (2014 - ongoing)

-          NIAS Lorentz Advisory Board (2015 – ongoing)

-          The Royal Netherlands Academy of Arts and Sciences (KNAW): The Young Academy (De Jonge Akademie) (2014-2019)

-          Dutch Association for Clinical Genetics: Ethics Committee (2013 – ongoing)

-          National Indication Committee for Preimplantation Genetic Diagnosis (2012 – ongoing)

-          Member Research Ethics Committee (METC) UMC Utrecht

-          Member of UMC Utrecht Ethics Committee on Reproductive Medicine

-          September 2008: Academic Visitor at the Mitochondrial Research Group, the Medical School, University of Newcastle-upon-Tyne, UK

Fellowship and Awards

-          Dutch Cancer Society KWF grant: “An empirical ethics study to introduce next-generation DNA sequencing into cancer care in a responsible way” (2014-2017)

-          University Medical Center Utrecht Strategic Program Associate Professorship grant (2014)

-          The Netherlands Organisation for Health Research and Development ZonMw VENI grant: “Ethics of translational stem cell research: moving pluripotent stem cells to the clinic” (2012-2015)

-          BioMedical Materials Program (BMM): “Regenerative Medicine and early intervention in intervertebral disc disease: ethics from bench to bedside” (2011-2014)

-          The Netherlands Organisation for Health Research and Development ZonMw Program Priority Medicines for Children: “To store or not to store? A normative analysis of consent in pediatric biobanks” ((2011-2014)

-          The Netherlands Organisation for Health Research and Development ZonMw Program Ethics & Health Care: “Research ethics in genomics studies: towards a protocol for returning individual genetic data to research participants” (2010-2011)

-          European Neuromuscular Centre International Workshop: grant to organize an international expert meeting: the 174th ENMC international workshop on Applying Pre-implantation Genetic Diagnosis to mtDNA disease” (Naarden, 19-21 March, 2010)

Research Output (127)

How digital health affects the patient-physician relationship:An empirical-ethics study into the perspectives and experiences in obstetric care

Jongsma K. R., Bekker M. N., Haitjema S., Bredenoord A. L. Aug 2021, In: Pregnancy Hypertension. 25 , p. 81-86 6 p.

Recognizing the ethical implications of stem cell research:A call for broadening the scope

Assen Lars S., Jongsma Karin R., Isasi Rosario, Tryfonidou Marianna A., Bredenoord Annelien L. 13 Jul 2021, In: Stem Cell Reports. 16 , p. 1656-1661 6 p.

Mini-gut feelings:Perspectives of people with cystic fibrosis on the ethics and governance of organoid biobanking

Lensink Michael A., Boers Sarah N., M Gulmans Vincent A., Jongsma Karin R., Bredenoord Annelien L. 7 Apr 2021, In: Personalized Medicine. 18 , p. 241-254 14 p.

Responsible Research with Human Tissues:The Need for Reciprocity Toward Both Collectives and Individuals

Lensink Michael A, Jongsma Karin R, Boers Sarah N, van Delden Johannes J M, Bredenoord Annelien L 3 Apr 2021, In: The American Journal of Bioethics. 21 , p. 75-78 4 p.

Publisher Correction: LifeTime and improving European healthcare through cell-based interceptive medicine

Rajewsky Nikolaus, Almouzni Geneviève, Gorski Stanislaw A., Aerts Stein, Amit Ido, Bertero Michela G., Bock Christoph, Bredenoord Annelien L., Cavalli Giacomo, Chiocca Susanna, Clevers Hans, De Strooper Bart, Eggert Angelika, Ellenberg Jan, Fernández Xosé M., Figlerowicz Marek, Gasser Susan M., Hubner Norbert, Kjems Jørgen, Knoblich Jürgen A., Krabbe Grietje, Lichter Peter, Linnarsson Sten, Marine Jean Christophe, Marioni John C., Marti-Renom Marc A., Netea Mihai G., Nickel Dörthe, Nollmann Marcelo, Novak Halina R., Parkinson Helen, Piccolo Stefano, Pinheiro Inês, Pombo Ana, Popp Christian, Reik Wolf, Roman-Roman Sergio, Rosenstiel Philip, Schultze Joachim L., Stegle Oliver, Tanay Amos, Testa Giuseppe, Thanos Dimitris, Theis Fabian J., Torres-Padilla Maria Elena, van Oudenaarden Alexander, Bruining Hilgo, Jongsma Karin R., Pasterkamp R. Jeroen, van Oudenaarden Alexander, 1 Apr 2021, In: Nature. 592 , p. E8

Experts' moral views on gene drive technologies:a qualitative interview study

de Graeff N., Jongsma Karin R., Bredenoord Annelien L. 8 Mar 2021, In: BMC Medical Ethics. 22 , p. 1-15 1 p.

Scrutinizing Privacy in Multi-Omics Research:How to Provide Ethical Grounding for the Identification of Privacy-Relevant Data Properties

Safarlou Caspar Willem, Bredenoord A.L., Vermeulen Roel, Jongsma Karin 2021, In: The American Journal of Bioethics. 21 , p. 73-75 3 p.

Organoids for personalized treatment of Cystic Fibrosis:Professional perspectives on the ethics and governance of organoid biobanking

Lensink Michael A, Boers Sarah N, Jongsma Karin R, Carter Sarah E, van der Ent Cornelis K, Bredenoord Annelien L 7 Dec 2020, In: Journal of Cystic Fibrosis. 20 , p. 443-451 9 p.

Modeling human embryogenesis: embryo-like structures spark ethical and policy debate:embryo-like structures spark ethical and policy debate

Pereira Daoud Ana M, Popovic Mina, Dondorp Wybo J, Trani Bustos Marc, Bredenoord Annelien L, Chuva de Sousa Lopes Susana M, van den Brink Susanne C, Roelen Bernard A J, de Wert Guido M W R, Heindryckx Björn 1 Nov 2020, In: Human Reproduction Update. 26 , p. 779-798 20 p.

From deficit to dialogue in science communication:The dialogue communication model requires additional roles from scientists

Reincke Cathelijne M., Bredenoord Annelien L., van Mil Marc H.W. 3 Sep 2020, In: EMBO Reports. 21 , p. 1-4

All research output

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