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prof. dr. J.M. Beekman

prof. dr. J.M. Beekman

Full Professor

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Research Output (99)

In-depth Characterization of Vaccine Breakthrough Infections With SARS-CoV-2 Among Health Care Workers in a Dutch Academic Medical Center

Rümke Lidewij W, Groenveld Femke C, van Os Yvonne M G, Praest Patrique, Tanja Anniek A N, de Jong Dorien T C M, Symons Jori, Schuurman Rob, Reinders Tessa, Hofstra L Marije, Nierkens Stefan, Thijsen Steven F T, Heron Michiel, Lebbink Robert-Jan, Beekman Jeffrey M, Nijhuis Monique, Wensing Annemarie M J Jan 2022, In: Open forum infectious diseases. 9 , p. 1-6

Prediction of Real-World Long-Term Outcomes of People with CF Homozygous for the F508del Mutation Treated with CFTR Modulators

Muilwijk Danya, Bierlaagh Marlou, van Mourik Peter, Kraaijkamp Jasmijn, van der Meer Renske, van den Bor Rutger, Heijerman Harry, Eijkemans René, Beekman Jeffrey, van der Ent Kors 16 Dec 2021, In: Journal of Personalized Medicine. 11 , p. 1-12

Evaluating CRISPR-based prime editing for cancer modeling and CFTR repair in organoids

Geurts Maarten H., de Poel Eyleen, Pleguezuelos-Manzano Cayetano, Oka Rurika, Carrillo Léo, Andersson-Rolf Amanda, Boretto Matteo, Brunsveld Jesse E., van Boxtel Ruben, Beekman Jeffrey M., Clevers Hans Oct 2021, In: Life Science Alliance. 4

CFTR Rescue in Intestinal Organoids with GLPG/ABBV-2737, ABBV/GLPG-2222 and ABBV/GLPG-2451 Triple Therapy

de Poel Eyleen, Spelier Sacha, Korporaal Ricardo, Lai Ka Wai, Boj Sylvia F., Conrath Katja, van der Ent Cornelis K., Beekman Jeffrey M. 15 Sep 2021, In: Frontiers in Molecular Biosciences. 8

A new era for people with cystic fibrosis

Bierlaagh Marlou C., Muilwijk Danya, Beekman Jeffrey M., van der Ent Cornelis K. Sep 2021, In: European Journal of Pediatrics. 180 , p. 2731-2739 9 p.

Breast development in a 7 year old girl with CF treated with ivacaftor:An indication for personalized dosing?

Jeyaratnam Joshena, van der Meer Renske, Berkers Gitte, Heijerman Harry Gm, Beekman Jeffrey M, van der Ent Cornelis K 23 Jun 2021, In: Journal of Cystic Fibrosis. 20 , p. e63-e66

Clinical effects of the three CFTR potentiator treatments curcumin, genistein and ivacaftor in patients with the CFTR-S1251N gating mutation

Berkers Gitte, van der Meer Renske, van Mourik Peter, Vonk Annelotte M, Kruisselbrink Evelien, Suen Sylvia Wf, Heijerman Harry Gm, Majoor Christof J, Koppelman Gerard H, Roukema Jolt, Janssens Hettie M, de Rijke Yolanda B, Kemper E Marleen, Beekman Jeffrey M, van der Ent Cornelis K, de Jonge Hugo R Nov 2020, In: Journal of Cystic Fibrosis. 19 , p. 955-961 7 p.

R117H-CFTR function and response to VX-770 correlate with mRNA and protein expression in intestinal organoids

Van Mourik Peter, van Haaren Paul, Kruisselbrink Evelien, Korkmaz Cemil, Janssens Hettie M., de Winter – de Groot Karin M., van der Ent Cornelis K., Hagemeijer Marne C., Beekman Jeffrey M. Sep 2020, In: Journal of Cystic Fibrosis. 19 , p. 728-732 5 p.

Protocol for Application, Standardization and Validation of the Forskolin-Induced Swelling Assay in Cystic Fibrosis Human Colon Organoids

Vonk Annelotte M, van Mourik Peter, Ramalho Anabela S, Silva Iris A L, Statia Marvin, Kruisselbrink Evelien, Suen Sylvia W F, Dekkers Johanna F, Vleggaar Frank P, Houwen Roderick H J, Mullenders Jasper, Boj Sylvia F, Vries Robert, Amaral Margarida D, de Boeck Kris, van der Ent Cornelis K, Beekman Jeffrey M 19 Jun 2020, In: STAR protocols. 1 31 p.

CRISPR-Based Adenine Editors Correct Nonsense Mutations in a Cystic Fibrosis Organoid Biobank

Geurts Maarten H., de Poel Eyleen, Amatngalim Gimano D., Oka Rurika, Meijers Fleur M., Kruisselbrink Evelien, van Mourik Peter, Berkers Gitte, de Winter-de Groot Karin M., Michel Sabine, Muilwijk Danya, Aalbers Bente L., Mullenders Jasper, Boj Sylvia F., Suen Sylvia W.F., Brunsveld Jesse E., Janssens Hettie M., Mall Marcus A., Graeber Simon Y., van Boxtel Ruben, van der Ent Cornelis K., Beekman Jeffrey M., Clevers Hans 2 Apr 2020, In: Cell stem cell. 26 , p. 503-510.e7

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